Hub : Traits : Delay discounting water rate 12 sec :

chr1:140,614,300-142,727,457

Trait: Delay discounting water rate 12 sec

Best TWAS P=7.984108e-08 · Best GWAS P=1.630892e-06 conditioned to 0.4385941

Associated models

# Tissue Gene Modality RNA phenotype h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 BLA Ctsc alternative polyA ENSRNOT00000022342 0.07 0.0 blup 2518 0.01 5.1e-02 4.0 -5.4 8.0e-08 0.81 0.42 0.26 TRUE
2 BLA Ctsc alternative polyA ENSRNOT00000097085 0.07 0.0 blup 2518 0.02 3.2e-02 -4.5 5.4 8.2e-08 -0.84 0.40 0.27 FALSE
3 Brain Grm5 gene expression ENSRNOG00000016429 0.16 0.1 lasso 6 0.15 5.3e-14 4.2 -5.2 2.0e-07 0.73 0.66 0.34 FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.