Best TWAS P=2.708085e-07 · Best GWAS P=5.069331e-07 conditioned to 0.09175488
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Acvr1c | intron excision ratio | chr3:42841102:42861024 | 0.05 | 0.02 | blup | 1465 | 0.03 | 0.00057 | 3.7 | -5.1 | 2.7e-07 | 0.77 | 0.7 | 0.23 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.