Best TWAS P=3.085433e-08 · Best GWAS P=0.02770984 conditioned to 0.3388371
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL | Ndrg3 | intron excision ratio | chr3:145550705:145552145 | 0.62 | 0.06 | blup | 1140 | 0.09 | 1.5e-07 | 2 | -5.5 | 3.1e-08 | -0.54 | 0.04 | 0.13 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.