Best TWAS P=6.087632e-14 · Best GWAS P=0.03616566 conditioned to 0.0005980733
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | Snx16 | gene expression | ENSRNOG00000009953 | 0.11 | 0.04 | enet | 157 | 0.06 | 1.2e-07 | -0.47 | 7.5 | 6.1e-14 | -0.63 | 0.06 | 0.03 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.