Best TWAS P=1.413338e-07 · Best GWAS P=2.868166e-07 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | BLA | Nploc4 | mRNA stability | ENSRNOG00000036698 | 0.09 | 0.07 | enet | 6 | 0.08 | 4.5e-05 | -4.2 | 5.3 | 1.4e-07 | -0.95 | 0.43 | 0.56 | TRUE |
| 2 | NAcc | Slc38a10 | gene expression | ENSRNOG00000004604 | 0.83 | 0.64 | top1 | 1 | 0.64 | 1.9e-61 | -5.1 | 5.1 | 3.4e-07 | -0.97 | 0.12 | 0.88 | FALSE |
| 3 | NAcc | Cep131 | intron excision ratio | chr10:105364365:105366957 | 0.80 | 0.63 | blup | 1644 | 0.63 | 1.8e-60 | -5.1 | 5.2 | 2.2e-07 | -0.99 | 0.16 | 0.84 | FALSE |
| 4 | NAcc | Cep131 | intron excision ratio | chr10:105364365:105367085 | 0.79 | 0.63 | top1 | 1 | 0.63 | 4.9e-59 | -5.1 | -5.1 | 3.4e-07 | 0.96 | 0.12 | 0.88 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.