Best TWAS P=1.830453e-07 · Best GWAS P=4.759201e-08 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Liver | Kif16b | gene expression | ENSRNOG00000004951 | 0.21 | 0.17 | lasso | 12 | 0.18 | 3.7e-19 | 5.2 | -5.1 | 3.0e-07 | 0.96 | 0.32 | 0.68 | FALSE |
| 2 | Liver | Snrpb2 | intron excision ratio | chr3:130399832:130400989 | 0.06 | 0.03 | blup | 1963 | 0.03 | 2.4e-04 | -5.0 | -5.1 | 3.1e-07 | 0.97 | 0.45 | 0.55 | FALSE |
| 3 | NAcc | Otor | gene expression | ENSRNOG00000028721 | 0.04 | 0.01 | top1 | 1 | 0.01 | 5.2e-02 | 5.2 | -5.2 | 1.8e-07 | 0.97 | 0.07 | 0.05 | TRUE |
| 4 | PL | Snrpb2 | gene expression | ENSRNOG00000004967 | 0.12 | 0.10 | enet | 9 | 0.11 | 1.3e-08 | 4.9 | 5.1 | 3.3e-07 | -0.98 | 0.49 | 0.51 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.