chr3:125,092,191-129,080,200

Trait: BMI without tail

Best TWAS P = 4.25e-09 · Best GWAS P= 2.48e-08 conditioned to 3.17e-02

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
BLA Pla2g4b alternative TSS XM_006234775.4 0.04 1495 0.02 4.6e-02 5.23 1.72e-07 0.3 FALSE
BLA LOC134486139 gene expression LOC134486139 0.5 106 0.45 4.5e-26 -5.44 5.44e-08 0.2 FALSE
BLA Mapkbp1 gene expression Mapkbp1 0.19 27 0.13 2.9e-07 5.34 9.15e-08 0.66 FALSE
BLA Bahd1 mRNA stability Bahd1 0.12 1 0.05 1.0e-03 -5.46 4.84e-08 0.17 FALSE
IC Lrrc57 alternative TSS XM_006234778.4 0.1 1764 0.04 6.5e-03 -5.23 1.68e-07 0.43 FALSE
IC Lrrc57 alternative TSS XM_006234778.4 0.08 6 0.04 9.7e-03 5.47 4.40e-08 0.38 FALSE
IL Pak6 mRNA stability Pak6 0.18 1 0.07 9.7e-03 5.52 3.46e-08 0.08 FALSE
Liver Tmem62 intron excision ratio chr3_128399842_128402601 0.09 9 0.02 4.7e-03 -5.36 8.52e-08 0.82 FALSE
NAcc Ganc intron excision ratio chr3_127807634_127809474 0.02 1611 0.01 2.2e-03 -5.25 1.52e-07 0.46 FALSE
NAcc Ivd mRNA stability Ivd 0.05 1870 0.04 5.2e-07 -5.25 1.54e-07 0.43 FALSE
PL Rmdn3 gene expression Rmdn3 0.07 1 0.06 1.9e-07 5.23 1.68e-07 0.94 FALSE
PL Ivd mRNA stability Ivd 0.03 1870 0.01 2.5e-02 -5.34 9.29e-08 0.56 FALSE
pVTA Ganc mRNA stability Ganc 0.48 106 0.1 1.6e-08 -5.87 4.25e-09 0.38 TRUE