Best TWAS P = 4.25e-09 · Best GWAS P= 2.48e-08 conditioned to 3.17e-02
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| BLA | Pla2g4b | alternative TSS | XM_006234775.4 | 0.04 | 1495 | 0.02 | 4.6e-02 | 5.23 | 1.72e-07 | 0.3 | FALSE |
| BLA | LOC134486139 | gene expression | LOC134486139 | 0.5 | 106 | 0.45 | 4.5e-26 | -5.44 | 5.44e-08 | 0.2 | FALSE |
| BLA | Mapkbp1 | gene expression | Mapkbp1 | 0.19 | 27 | 0.13 | 2.9e-07 | 5.34 | 9.15e-08 | 0.66 | FALSE |
| BLA | Bahd1 | mRNA stability | Bahd1 | 0.12 | 1 | 0.05 | 1.0e-03 | -5.46 | 4.84e-08 | 0.17 | FALSE |
| IC | Lrrc57 | alternative TSS | XM_006234778.4 | 0.1 | 1764 | 0.04 | 6.5e-03 | -5.23 | 1.68e-07 | 0.43 | FALSE |
| IC | Lrrc57 | alternative TSS | XM_006234778.4 | 0.08 | 6 | 0.04 | 9.7e-03 | 5.47 | 4.40e-08 | 0.38 | FALSE |
| IL | Pak6 | mRNA stability | Pak6 | 0.18 | 1 | 0.07 | 9.7e-03 | 5.52 | 3.46e-08 | 0.08 | FALSE |
| Liver | Tmem62 | intron excision ratio | chr3_128399842_128402601 | 0.09 | 9 | 0.02 | 4.7e-03 | -5.36 | 8.52e-08 | 0.82 | FALSE |
| NAcc | Ganc | intron excision ratio | chr3_127807634_127809474 | 0.02 | 1611 | 0.01 | 2.2e-03 | -5.25 | 1.52e-07 | 0.46 | FALSE |
| NAcc | Ivd | mRNA stability | Ivd | 0.05 | 1870 | 0.04 | 5.2e-07 | -5.25 | 1.54e-07 | 0.43 | FALSE |
| PL | Rmdn3 | gene expression | Rmdn3 | 0.07 | 1 | 0.06 | 1.9e-07 | 5.23 | 1.68e-07 | 0.94 | FALSE |
| PL | Ivd | mRNA stability | Ivd | 0.03 | 1870 | 0.01 | 2.5e-02 | -5.34 | 9.29e-08 | 0.56 | FALSE |
| pVTA | Ganc | mRNA stability | Ganc | 0.48 | 106 | 0.1 | 1.6e-08 | -5.87 | 4.25e-09 | 0.38 | TRUE |