chr1:201,865,024-205,361,167

Trait: BMI with tail

Best TWAS P=1.97e-09 · Best GWAS P=1.08e-08 conditioned to 2.99e-01

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Ccdc85b gene expression Ccdc85b 0.04 1 0.02 1.0e-03 5.31 1.09e-07 0.34 FALSE
Adipose Ehbp1l1 gene expression Ehbp1l1 0.31 1415 0.21 1.7e-22 -5.57 2.61e-08 0.57 FALSE
Adipose Fosl1 gene expression Fosl1 0.08 43 0.05 5.7e-06 5.35 8.94e-08 0.86 FALSE
Adipose Naaladl1 gene expression Naaladl1 0.22 1 0.15 1.8e-16 -5.37 8.04e-08 0.76 FALSE
Adipose Ovol1 gene expression Ovol1 0.12 1327 0.04 4.3e-05 -5.29 1.25e-07 0.38 FALSE
Adipose Pcnx3 gene expression Pcnx3 0.13 1 0.09 5.9e-10 -5.31 1.09e-07 0.71 FALSE
Adipose Cox8a mRNA stability Cox8a 0.04 1339 0.02 5.4e-03 5.27 1.35e-07 0.58 FALSE
Adipose Rpl37-ps2 mRNA stability Rpl37-ps2 0.09 22 0.05 5.0e-06 -5.53 3.22e-08 0.82 FALSE
Adipose Scyl1 mRNA stability Scyl1 0.15 1 0.1 1.9e-11 5.42 6.09e-08 0.8 FALSE
BLA Fermt3 alternative polyA XM_006230811.4 0.1 1 0 2.1e-01 -5.24 1.57e-07 0.05 FALSE
BLA Fermt3 alternative polyA XM_039079706.1 0.11 1 0 1.8e-01 5.24 1.57e-07 0.05 FALSE
BLA Snx32 alternative polyA XM_039094858.1 0.08 1306 0.07 8.7e-05 5.41 6.17e-08 0.66 FALSE
BLA Kcnk4 alternative TSS XM_008760056.3 0.13 1364 0.08 3.9e-05 -5.36 8.41e-08 0.84 FALSE
BLA Capn1 gene expression Capn1 0.24 4 0.13 1.2e-07 -5.43 5.67e-08 0.67 FALSE
BLA Kcnk4 gene expression Kcnk4 0.36 1364 0.26 4.2e-14 5.37 7.72e-08 0.86 FALSE
BLA Naaladl1 gene expression Naaladl1 0.71 1 0.52 6.3e-32 -5.42 6.09e-08 0.81 FALSE
BLA Ovol1 gene expression Ovol1 0.25 1327 0.13 1.1e-07 -5.37 7.99e-08 0.88 FALSE
BLA Rps6ka4 gene expression Rps6ka4 0.43 224 0.25 7.5e-14 -5.35 9.02e-08 0.87 FALSE
BLA Snx15 gene expression Snx15 0.12 117 0.07 1.7e-04 5.51 3.68e-08 0.73 FALSE
BLA Kcnk4 isoform ratio XM_008760056.3 0.12 1 0.1 8.3e-06 5.44 5.31e-08 0.55 FALSE
BLA Rtn3 isoform ratio NM_001009953.3 0.16 39 0.11 1.0e-06 -5.22 1.76e-07 0.82 FALSE
Brain Snx32 alternative polyA XM_039094858.1 0.08 1 0.07 2.0e-07 -5.46 4.67e-08 0.88 FALSE
Brain Snx32 alternative polyA XM_039094864.1 0.12 1 0.11 1.9e-10 5.61 2.03e-08 0.95 FALSE
Brain Kcnk4 alternative TSS XM_008760056.3 0.18 5 0.13 1.1e-11 -5.76 8.34e-09 0.86 FALSE
Brain Kcnk4 gene expression Kcnk4 0.33 11 0.26 3.6e-24 -5.77 7.73e-09 0.86 FALSE
Brain Naaladl1 gene expression Naaladl1 0.73 26 0.56 4.1e-62 5.64 1.69e-08 0.76 FALSE
Brain Rps6ka4 gene expression Rps6ka4 0.08 1 0.04 9.7e-05 -5.44 5.31e-08 0.3 FALSE
Brain Sac3d1 gene expression Sac3d1 0.15 1636 0.06 3.2e-06 5.25 1.56e-07 0.84 FALSE
Brain Snx15 gene expression Snx15 0.21 71 0.17 1.2e-15 5.59 2.31e-08 0.74 FALSE
Brain Snx32 gene expression Snx32 0.14 147 0.11 1.8e-10 5.41 6.13e-08 0.72 FALSE
Brain Kcnk4 isoform ratio XM_008760056.3 0.17 5 0.12 3.6e-11 -5.81 6.39e-09 0.85 FALSE
Brain Snx32 isoform ratio XM_341993.9 0.07 1306 0.07 6.8e-07 -5.44 5.33e-08 0.67 FALSE
Brain Rpl37-ps2 intron excision ratio chr1_202839369_202840008 0.13 10 0.08 3.4e-08 -5.5 3.85e-08 0.72 FALSE
Brain Rpl37-ps2 intron excision ratio chr1_202839369_202855817 0.12 2 0.11 2.9e-10 -5.2 1.97e-07 0.72 FALSE
Brain Cox8a mRNA stability Cox8a 0.12 10 0.1 9.2e-10 -5.79 7.10e-09 0.89 FALSE
Brain Kcnk4 mRNA stability Kcnk4 0.12 6 0.07 1.7e-07 -5.71 1.12e-08 0.82 FALSE
Brain Rpl37-ps2 mRNA stability Rpl37-ps2 0.33 142 0.22 1.5e-20 5.56 2.63e-08 0.72 FALSE
Brain Snx32 mRNA stability Snx32 0.06 1 0.04 6.2e-05 5.39 7.04e-08 0.49 FALSE
Eye Kcnk4 gene expression Kcnk4 0.53 10 0.09 1.8e-02 5.73 1.03e-08 0.13 FALSE
IL Naaladl1 gene expression Naaladl1 0.67 1 0.21 9.4e-06 -5.22 1.78e-07 0.18 FALSE
IL Ovol1 gene expression Ovol1 0.33 1 0.14 3.6e-04 5.39 6.87e-08 0.09 FALSE
IL Rps6ka4 gene expression Rps6ka4 0.19 304 0.08 5.0e-03 -5.5 3.76e-08 0.32 FALSE
LHb Fermt3 alternative TSS NM_001127543.1 0.2 75 0.12 9.0e-04 -5.21 1.90e-07 0.02 FALSE
LHb Flrt1 gene expression Flrt1 0.4 1 0.19 3.2e-05 5.36 8.38e-08 0.08 FALSE
LHb Naaladl1 gene expression Naaladl1 0.2 54 0.11 1.3e-03 -5.39 7.13e-08 0.56 FALSE
LHb Snx15 gene expression Snx15 0.72 5 0.12 7.2e-04 -5.32 1.06e-07 0.6 FALSE
Liver Otub1 gene expression Otub1 0.33 22 0.23 2.1e-25 -5.54 3.00e-08 0.88 FALSE
Liver Macrod1 mRNA stability Macrod1 0.06 1 0.04 5.2e-05 5.45 4.96e-08 0.28 FALSE
Liver Pcnx3 mRNA stability Pcnx3 0.05 1404 0.02 1.2e-03 -5.68 1.36e-08 0.82 FALSE
NAcc Syvn1 alternative TSS XM_006230852.4 0.02 7 0.01 6.5e-03 5.61 1.97e-08 0.62 FALSE
NAcc Naaladl1 gene expression Naaladl1 0.67 19 0.49 1.5e-64 5.42 6.12e-08 0.76 FALSE
NAcc Sac3d1 gene expression Sac3d1 0.39 1 0.25 6.2e-29 -5.43 5.64e-08 0.82 FALSE
NAcc Macrod1 isoform ratio NM_139337.2 0.03 1347 0.02 3.8e-03 -5.2 1.99e-07 0.7 FALSE
NAcc Snx32 isoform ratio XM_039094858.1 0.12 1306 0.11 1.9e-12 5.21 1.92e-07 0.57 FALSE
NAcc Rpl37-ps2 intron excision ratio chr1_202839369_202840008 0.08 1 0.05 4.2e-06 -5.34 9.11e-08 0.78 FALSE
NAcc Rpl37-ps2 intron excision ratio chr1_202839369_202855814 0.04 1313 0.02 4.3e-03 -5.37 7.74e-08 0.77 FALSE
NAcc Naaladl1 mRNA stability Naaladl1 0.06 33 0.06 4.5e-07 -5.95 2.73e-09 0.79 FALSE
NAcc Otub1 mRNA stability Otub1 0.08 1 0.06 1.6e-07 -5.31 1.08e-07 0.71 FALSE
NAcc Rpl37-ps2 mRNA stability Rpl37-ps2 0.12 62 0.12 1.2e-13 5.61 2.02e-08 0.67 FALSE
OFC Kcnk4 gene expression Kcnk4 0.34 24 0.13 4.5e-04 5.36 8.46e-08 0.58 FALSE
OFC Naaladl1 gene expression Naaladl1 0.61 1 0.25 1.3e-06 -5.22 1.78e-07 0.12 FALSE
OFC Ovol1 gene expression Ovol1 0.34 1 0.17 6.3e-05 5.21 1.84e-07 0.07 FALSE
PL Macrod1 alternative polyA XM_039099901.1 0.05 1 0.02 1.6e-03 -5.72 1.08e-08 0.22 FALSE
PL Naa40 alternative polyA NM_001108518.1 0.06 1 0.05 3.6e-06 -5.4 6.72e-08 0.68 FALSE
PL Naa40 alternative polyA XM_039084082.1 0.06 1 0.05 1.7e-06 5.4 6.72e-08 0.73 FALSE
PL Naa40 alternative polyA NM_001108518.1 0.06 1 0.05 2.6e-06 -5.4 6.72e-08 0.71 FALSE
PL Naa40 alternative polyA XM_039084072.1 0.06 1 0.05 1.5e-06 5.4 6.72e-08 0.74 FALSE
PL Arl2 alternative TSS XM_006230899.3 0.03 1 0.01 8.7e-03 5.42 6.09e-08 0.04 FALSE
PL Kcnk4 alternative TSS XM_008760056.3 0.12 6 0.11 8.6e-12 -5.59 2.22e-08 0.87 FALSE
PL Kcnk4 alternative TSS NM_053804.3 0.13 1364 0.1 1.4e-10 5.21 1.86e-07 0.88 FALSE
PL Kcnk4 alternative TSS XM_008760055.3 0.12 1364 0.09 2.4e-10 -5.22 1.81e-07 0.88 FALSE
PL Catsperz gene expression Catsperz 0.05 1 0.02 2.8e-03 -5.29 1.19e-07 0.09 FALSE
PL Efemp2 gene expression Efemp2 0.05 1 0.05 4.0e-06 -5.39 7.04e-08 0.88 FALSE
PL Kcnk4 gene expression Kcnk4 0.19 1364 0.14 1.9e-15 5.49 4.10e-08 0.86 FALSE
PL Naaladl1 gene expression Naaladl1 0.67 46 0.51 2.1e-65 5.45 5.07e-08 0.76 FALSE
PL Ovol1 gene expression Ovol1 0.31 14 0.28 3.0e-31 -5.46 4.77e-08 0.7 FALSE
PL Pcnx3 gene expression Pcnx3 0.06 65 0.04 5.4e-05 -6 1.97e-09 0.83 TRUE
PL Rps6ka4 gene expression Rps6ka4 0.18 1 0.12 2.7e-13 -5.53 3.16e-08 0.89 FALSE
PL Yif1a gene expression Yif1a 0.05 1 0.03 1.4e-04 5.34 9.11e-08 0.82 FALSE
PL Kcnk4 isoform ratio XM_008760056.3 0.1 4 0.09 2.2e-10 -5.49 4.07e-08 0.84 FALSE
PL Snx32 isoform ratio XM_341993.9 0.02 1306 0.02 2.6e-03 -5.3 1.19e-07 0.53 FALSE
PL Kcnk4 intron excision ratio chr1_204120828_204124788 0.04 1 0.02 1.2e-03 -5.29 1.21e-07 0.11 FALSE
PL Nrxn2 intron excision ratio chr1_203763525_203780407 0.03 1 0.01 2.5e-02 5.45 4.96e-08 0.07 FALSE
PL Rpl37-ps2 intron excision ratio chr1_202839369_202840008 0.32 28 0.22 9.2e-24 5.26 1.45e-07 0.73 FALSE
PL Scyl1 mRNA stability Scyl1 0.04 1 0.02 1.5e-03 -5.38 7.54e-08 0.12 FALSE
pVTA Snx32 alternative polyA XM_039094829.1 0.1 1306 0.05 4.1e-03 5.38 7.41e-08 0.65 FALSE
pVTA Snx32 alternative polyA XM_341993.9 0.15 1 0.09 9.0e-05 5.18 2.27e-07 0.19 FALSE
pVTA Fosl1 gene expression Fosl1 0.41 128 0.21 1.4e-09 5.19 2.06e-07 0.82 FALSE
pVTA Naaladl1 gene expression Naaladl1 0.45 1 0.25 3.3e-11 -5.68 1.36e-08 0.95 FALSE
pVTA Snx15 gene expression Snx15 0.56 11 0.2 6.8e-09 -5.41 6.19e-08 0.79 FALSE
pVTA Snx32 gene expression Snx32 0.14 1 0.05 2.3e-03 -5.61 2.03e-08 0.61 FALSE
pVTA Rpl37-ps2 intron excision ratio chr1_202839369_202840008 0.15 1313 0.07 4.6e-04 5.24 1.65e-07 0.82 FALSE
pVTA Rpl37-ps2 intron excision ratio chr1_202839369_202855817 0.17 1 0.16 2.2e-07 5.18 2.18e-07 0.48 FALSE
RMTg Znrd2 isoform ratio NM_001109537.2 0.25 54 0.13 2.3e-04 -5.38 7.65e-08 0.68 FALSE
RMTg Sipa1 mRNA stability Sipa1 0.16 1376 0.1 1.7e-03 -5.29 1.25e-07 0.52 FALSE