Best TWAS P=3.111771e-08 · Best GWAS P=2.226055e-05 conditioned to 0.6638014
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Liver | Ptgdr2 | gene expression | ENSRNOG00000036631 | 0.46 | 0.02 | blup | 2343 | 0.06 | 2.6e-07 | -3.3 | -5.5 | 3.1e-08 | -0.71 | 0.37 | 0.19 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.