Hub : Traits : BMI with tail : →

chr1:201,865,024-205,361,167

Trait: BMI with tail

Best TWAS P=7.147148e-09 · Best GWAS P=1.081408e-08 conditioned to NaN

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Drap1	gene expression	ENSRNOG00000020527	0.10	0.05	top1	1	0.05	1.8e-06	5.3	5.3	1.1e-07	0.57	0.08	0.91	FALSE
2	Adipose	Fosl1	gene expression	ENSRNOG00000020552	0.11	0.02	blup	1189	0.03	2.0e-04	5.3	-5.3	9.3e-08	-0.77	0.13	0.87	FALSE
3	Adipose	Pcnx3	gene expression	ENSRNOG00000020742	0.15	0.09	top1	1	0.09	3.6e-10	5.3	5.3	1.1e-07	0.67	0.29	0.71	FALSE
4	Adipose	Naaladl1	gene expression	ENSRNOG00000021000	0.23	0.16	top1	1	0.16	9.0e-18	5.4	5.4	8.0e-08	0.70	0.23	0.76	FALSE
5	Adipose	Fermt3	gene expression	ENSRNOG00000021161	0.04	0.03	top1	1	0.03	6.4e-04	5.4	-5.4	5.8e-08	-0.89	0.05	0.06	FALSE
6	Adipose	Cdca5	gene expression	ENSRNOG00000046635	0.07	0.04	top1	1	0.04	7.6e-05	5.4	-5.4	5.8e-08	-0.86	0.13	0.50	FALSE
7	Adipose	Ehbp1l1	gene expression	ENSRNOG00000056038	0.32	0.16	blup	1413	0.21	1.9e-23	5.6	-5.6	1.9e-08	-0.81	0.20	0.80	FALSE
8	Adipose	Ccdc85b	gene expression	ENSRNOG00000070266	0.03	0.01	top1	1	0.01	1.1e-02	5.3	-5.3	1.1e-07	-0.68	0.04	0.06	FALSE
9	Adipose	Snx32	isoform ratio	ENSRNOT00000096559	0.05	0.02	blup	1299	0.03	3.0e-04	-3.0	5.2	2.6e-07	0.69	0.27	0.65	FALSE
10	Adipose	Znrd2	intron excision ratio	chr1:203018382:203018914	0.05	0.01	blup	1413	0.01	1.4e-02	-3.0	5.1	3.5e-07	0.71	0.33	0.48	FALSE
11	Adipose	Scyl1	mRNA stability	ENSRNOG00000023668	0.15	0.10	top1	1	0.10	2.8e-11	5.4	-5.4	6.1e-08	-0.78	0.20	0.80	FALSE
12	BLA	Ovol1	gene expression	ENSRNOG00000020669	0.23	0.13	enet	22	0.14	1.0e-07	5.7	-5.8	7.1e-09	-0.92	0.11	0.89	TRUE
13	BLA	Naaladl1	gene expression	ENSRNOG00000021000	0.70	0.51	top1	1	0.51	4.3e-31	5.4	5.4	6.1e-08	0.77	0.19	0.81	FALSE
14	BLA	Rps6ka4	gene expression	ENSRNOG00000021117	0.39	0.23	enet	199	0.25	1.3e-13	5.6	5.6	2.3e-08	0.91	0.13	0.87	FALSE
15	BLA	Kcnk4	gene expression	ENSRNOG00000021140	0.33	0.18	blup	1370	0.21	1.1e-11	5.6	5.3	1.2e-07	0.86	0.14	0.86	FALSE
16	BLA	Ehbp1l1	gene expression	ENSRNOG00000056038	0.09	0.05	top1	1	0.05	1.3e-03	5.3	5.3	1.1e-07	0.72	0.09	0.13	FALSE
17	BLA	Naaladl1	isoform ratio	ENSRNOT00000054835	0.09	0.03	blup	1618	0.06	5.8e-04	5.4	-5.2	1.6e-07	-0.79	0.22	0.69	FALSE
18	BLA	Naaladl1	isoform ratio	ENSRNOT00000095018	0.08	0.03	blup	1618	0.06	6.8e-04	5.4	5.3	1.5e-07	0.79	0.22	0.68	FALSE
19	BLA	Otub1	isoform ratio	ENSRNOT00000114563	0.24	0.16	lasso	3	0.17	2.9e-09	5.6	-5.7	1.0e-08	-0.98	0.14	0.86	FALSE
20	BLA	Spindoc	isoform ratio	ENSRNOT00000034477	0.07	0.04	top1	1	0.04	5.2e-03	5.3	5.3	1.3e-07	0.95	0.08	0.10	FALSE
21	BLA	Spindoc	isoform ratio	ENSRNOT00000083157	0.08	0.05	top1	1	0.05	1.8e-03	5.3	-5.3	1.3e-07	-0.95	0.09	0.12	FALSE
22	BLA	Ehbp1l1	isoform ratio	ENSRNOT00000077526	0.06	0.04	blup	1413	0.04	1.9e-03	5.4	-5.6	2.4e-08	-0.81	0.30	0.60	FALSE
23	BLA	Nrxn2	intron excision ratio	chr1:203802213:203813559	0.08	0.03	top1	1	0.03	9.7e-03	5.3	-5.3	8.8e-08	-0.59	0.07	0.06	FALSE
24	Brain	Fosl1	gene expression	ENSRNOG00000020552	0.22	0.15	enet	112	0.16	2.4e-14	5.3	-5.1	3.3e-07	-0.77	0.12	0.88	FALSE
25	Brain	Ovol1	gene expression	ENSRNOG00000020669	0.23	0.10	blup	1323	0.13	1.8e-12	5.3	-5.2	1.7e-07	-0.72	0.30	0.70	FALSE
26	Brain	Pcnx3	gene expression	ENSRNOG00000020742	0.11	0.09	top1	1	0.09	8.6e-09	5.3	5.3	1.5e-07	0.80	0.35	0.64	FALSE
27	Brain	Naaladl1	gene expression	ENSRNOG00000021000	0.77	0.56	top1	1	0.56	2.0e-62	5.4	5.4	5.6e-08	0.73	0.18	0.82	FALSE
28	Brain	Sac3d1	gene expression	ENSRNOG00000021003	0.12	0.04	lasso	3	0.05	1.1e-05	5.4	5.5	3.7e-08	0.79	0.15	0.84	FALSE
29	Brain	Kcnk4	gene expression	ENSRNOG00000021140	0.28	0.17	lasso	12	0.21	1.7e-19	5.2	5.7	1.0e-08	0.22	0.22	0.78	TRUE
30	Brain	Otub1	gene expression	ENSRNOG00000021175	0.62	0.36	lasso	36	0.46	4.9e-47	5.5	-5.4	7.5e-08	-0.91	0.10	0.90	FALSE
31	Brain	Snx32	gene expression	ENSRNOG00000026527	0.17	0.15	blup	1299	0.16	1.8e-14	5.3	-5.5	4.2e-08	-0.80	0.28	0.72	FALSE
32	Brain	Naaladl1	isoform ratio	ENSRNOT00000054835	0.25	0.11	top1	1	0.11	4.7e-10	5.4	-5.4	5.6e-08	-0.78	0.18	0.82	FALSE
33	Brain	Naaladl1	isoform ratio	ENSRNOT00000095018	0.25	0.11	top1	1	0.11	5.4e-10	5.4	5.4	5.6e-08	0.78	0.18	0.82	FALSE
34	Brain	Slc22a12	isoform ratio	ENSRNOT00000028665	0.06	0.02	blup	1509	0.02	2.6e-03	5.4	-5.2	2.1e-07	-0.80	0.18	0.74	TRUE
35	Brain	Slc22a12	isoform ratio	ENSRNOT00000092496	0.07	0.02	top1	1	0.02	2.4e-03	5.5	5.5	3.0e-08	0.57	0.05	0.34	FALSE
36	Brain	Macrod1	isoform ratio	ENSRNOT00000091465	0.09	0.11	lasso	1	0.11	3.0e-10	-2.9	5.6	2.5e-08	-0.27	1.00	0.00	TRUE
37	Brain	Otub1	isoform ratio	ENSRNOT00000114563	0.11	0.08	lasso	5	0.08	3.2e-08	5.2	-5.4	6.7e-08	-0.97	0.18	0.82	FALSE
38	Brain	Snx32	isoform ratio	ENSRNOT00000036745	0.12	0.10	top1	1	0.10	3.8e-09	5.4	-5.4	6.9e-08	-0.76	0.16	0.84	FALSE
39	Brain	Snx32	isoform ratio	ENSRNOT00000096559	0.14	0.11	top1	1	0.11	2.2e-10	5.4	5.4	6.9e-08	0.78	0.16	0.84	FALSE
40	Brain	Ehbp1l1	isoform ratio	ENSRNOT00000077526	0.07	0.03	blup	1413	0.05	2.2e-05	4.9	-5.1	3.2e-07	-0.68	0.56	0.43	FALSE
41	Brain	NA	intron excision ratio	chr1:203313183:203313863	0.06	0.04	top1	1	0.04	2.6e-04	5.4	5.4	6.5e-08	0.75	0.06	0.12	FALSE
42	Brain	Snx32	mRNA stability	ENSRNOG00000026527	0.07	0.03	top1	1	0.03	9.1e-04	5.3	-5.3	1.0e-07	-0.77	0.06	0.12	FALSE
43	Eye	Naaladl1	gene expression	ENSRNOG00000021000	0.41	0.10	enet	50	0.12	6.9e-03	5.3	5.5	4.9e-08	0.84	0.21	0.40	FALSE
44	IL	Ovol1	gene expression	ENSRNOG00000020669	0.25	0.03	blup	1320	0.06	1.2e-02	5.2	-5.4	7.0e-08	-0.75	0.29	0.46	FALSE
45	IL	Naaladl1	gene expression	ENSRNOG00000021000	0.69	0.16	lasso	11	0.21	7.9e-06	5.3	5.6	2.5e-08	0.85	0.24	0.75	FALSE
46	IL	Rtn3	intron excision ratio	chr1:204621909:204668857	0.38	0.14	top1	1	0.14	2.8e-04	5.5	5.5	3.2e-08	0.86	0.08	0.22	FALSE
47	IL	Pacs1	mRNA stability	ENSRNOG00000020350	0.22	0.01	top1	1	0.01	2.2e-01	5.2	-5.2	2.1e-07	-0.49	0.06	0.07	FALSE
48	LHb	Naaladl1	gene expression	ENSRNOG00000021000	0.28	0.13	enet	14	0.15	1.8e-04	5.3	5.3	9.2e-08	0.85	0.19	0.70	FALSE
49	LHb	Snx15	gene expression	ENSRNOG00000021007	0.55	0.14	top1	1	0.14	3.9e-04	5.3	-5.3	1.1e-07	-0.50	0.09	0.07	FALSE
50	LHb	Kcnk4	gene expression	ENSRNOG00000021140	0.18	0.01	blup	1367	0.07	7.7e-03	5.6	5.2	2.1e-07	0.82	0.20	0.48	FALSE
51	Liver	Macrod1	alternative polyA	ENSRNOT00000091465	0.20	0.07	enet	15	0.08	4.1e-09	5.1	5.2	1.8e-07	0.77	0.34	0.66	FALSE
52	Liver	Otub1	alternative polyA	ENSRNOT00000114563	0.16	0.08	enet	97	0.09	1.9e-10	-3.2	5.6	1.6e-08	0.89	1.00	0.00	FALSE
53	Liver	Macrod1	alternative TSS	ENSRNOT00000028749	0.05	0.03	top1	1	0.03	4.9e-04	5.4	5.4	6.7e-08	0.66	0.05	0.09	FALSE
54	Liver	Macrod1	alternative TSS	ENSRNOT00000106741	0.04	0.03	top1	1	0.03	6.5e-04	5.4	-5.4	6.7e-08	-0.68	0.05	0.07	FALSE
55	Liver	Znrd2	gene expression	ENSRNOG00000012736	0.05	0.02	top1	1	0.02	1.0e-03	5.3	5.3	1.1e-07	0.82	0.05	0.06	FALSE
56	Liver	Naaladl1	gene expression	ENSRNOG00000021000	0.07	0.06	top1	1	0.06	9.2e-07	5.3	5.3	9.7e-08	0.68	0.25	0.67	FALSE
57	Liver	Otub1	gene expression	ENSRNOG00000021175	0.26	0.18	lasso	27	0.19	1.1e-20	5.6	-5.8	8.9e-09	-0.98	0.12	0.88	FALSE
58	Liver	Ehbp1l1	gene expression	ENSRNOG00000056038	0.04	0.02	top1	1	0.02	5.5e-03	5.6	-5.6	2.7e-08	-0.77	0.04	0.07	FALSE
59	Liver	Pcnx3	mRNA stability	ENSRNOG00000020742	0.05	0.02	top1	1	0.02	3.1e-03	5.6	-5.6	2.7e-08	-0.80	0.06	0.38	FALSE
60	Liver	Otub1	mRNA stability	ENSRNOG00000021175	0.05	0.02	top1	1	0.02	1.0e-03	5.5	5.5	2.9e-08	0.95	0.06	0.31	FALSE
61	NAcc	Ovol1	gene expression	ENSRNOG00000020669	0.08	0.01	blup	1322	0.05	2.4e-04	4.6	-5.2	2.1e-07	-0.71	0.43	0.56	FALSE
62	NAcc	Naaladl1	gene expression	ENSRNOG00000021000	0.61	0.43	enet	134	0.46	1.1e-37	5.4	5.3	1.0e-07	0.76	0.24	0.76	FALSE
63	NAcc	Sac3d1	gene expression	ENSRNOG00000021003	0.36	0.23	top1	1	0.23	7.7e-17	5.4	5.4	5.3e-08	0.72	0.17	0.83	FALSE
64	NAcc	Otub1	gene expression	ENSRNOG00000021175	0.28	0.22	lasso	11	0.26	1.3e-19	5.6	-5.6	2.2e-08	-0.92	0.14	0.86	FALSE
65	NAcc	Snx32	isoform ratio	ENSRNOT00000096559	0.07	0.03	blup	1298	0.04	6.6e-04	5.4	5.5	3.4e-08	0.77	0.26	0.72	FALSE
66	NAcc	Ehbp1l1	isoform ratio	ENSRNOT00000077526	0.05	0.01	blup	1412	0.03	5.0e-03	4.6	-5.4	8.7e-08	-0.74	0.40	0.46	FALSE
67	NAcc	Efemp2	intron excision ratio	chr1:202783177:202783817	0.05	0.02	blup	1207	0.02	7.8e-03	3.6	5.2	1.7e-07	0.73	0.28	0.52	FALSE
68	NAcc	Dnajc4	intron excision ratio	chr1:204179906:204180400	0.06	0.04	top1	1	0.04	8.7e-04	5.6	5.6	2.5e-08	0.79	0.06	0.25	FALSE
69	NAcc	Otub1	mRNA stability	ENSRNOG00000021175	0.04	0.03	top1	1	0.03	1.8e-03	5.3	5.3	1.1e-07	0.88	0.05	0.06	FALSE
70	OFC	Ovol1	gene expression	ENSRNOG00000020669	0.25	0.16	top1	1	0.16	1.0e-04	5.4	-5.4	6.9e-08	-0.76	0.07	0.08	TRUE
71	OFC	Naaladl1	gene expression	ENSRNOG00000021000	0.63	0.25	lasso	22	0.26	7.8e-07	5.3	5.2	2.1e-07	0.69	0.32	0.66	FALSE
72	OFC	Naaladl1	isoform ratio	ENSRNOT00000054835	0.32	0.09	lasso	14	0.09	3.1e-03	4.9	-5.2	1.8e-07	-0.73	0.31	0.45	FALSE
73	PL	Yif1a	gene expression	ENSRNOG00000020201	0.07	0.03	top1	1	0.03	2.8e-03	5.3	-5.3	9.1e-08	-0.70	0.03	0.49	FALSE
74	PL	Fosl1	gene expression	ENSRNOG00000020552	0.06	0.04	blup	1188	0.04	4.2e-04	5.5	-5.3	1.4e-07	-0.77	0.16	0.76	FALSE
75	PL	Efemp2	gene expression	ENSRNOG00000020587	0.06	0.03	blup	1207	0.04	2.4e-04	4.9	5.3	1.2e-07	0.74	0.22	0.74	FALSE
76	PL	Ovol1	gene expression	ENSRNOG00000020669	0.34	0.29	lasso	12	0.30	8.9e-23	5.2	-5.3	9.0e-08	-0.77	0.31	0.69	FALSE
77	PL	Capn1	gene expression	ENSRNOG00000020935	0.26	0.10	top1	1	0.10	3.6e-08	5.6	-5.6	2.6e-08	-0.82	0.10	0.90	FALSE
78	PL	Naaladl1	gene expression	ENSRNOG00000021000	0.57	0.42	enet	111	0.45	5.2e-38	5.4	5.2	2.2e-07	0.76	0.27	0.73	FALSE
79	PL	Kcnk4	gene expression	ENSRNOG00000021140	0.09	0.03	blup	1367	0.05	7.1e-05	5.6	5.5	4.8e-08	0.94	0.15	0.84	FALSE
80	PL	Snx32	gene expression	ENSRNOG00000026527	0.07	0.01	blup	1298	0.04	3.1e-04	5.2	-5.3	1.4e-07	-0.77	0.28	0.70	FALSE
81	PL	Snx32	isoform ratio	ENSRNOT00000096559	0.10	0.05	blup	1298	0.07	6.4e-06	4.8	5.1	2.8e-07	0.74	0.36	0.63	FALSE
82	PL	Rtn3	intron excision ratio	chr1:204621909:204655272	0.17	0.13	lasso	11	0.16	6.8e-12	4.6	-5.3	9.1e-08	-0.71	0.44	0.56	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.