Best TWAS P=3.325659e-07 · Best GWAS P=2.980277e-07 conditioned to 0.05200754
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | NAcc | Mlip | gene expression | ENSRNOG00000005934 | 0.05 | 0.02 | top1 | 1 | 0.02 | 0.0082 | 5.1 | -5.1 | 3.3e-07 | -0.75 | 0.04 | 0.53 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.