Best TWAS P=1.193879e-07 · Best GWAS P=0.02108104 conditioned to 2.013702e-57
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL | Trim16 | gene expression | ENSRNOG00000003287 | 0.05 | 0.04 | enet | 334 | 0.04 | 0.00064 | -1.8 | -5.3 | 1.2e-07 | -0.9 | 0.16 | 0.07 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.