Best TWAS P=2.218574e-07 · Best GWAS P=0.2069056 conditioned to 0.05324069
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | LHb | Ccdc71 | isoform ratio | ENSRNOT00000074493 | 0.6 | 0.01 | enet | 223 | 0.22 | 4.8e-06 | 1.1 | 5.2 | 2.2e-07 | -0.13 | 0.01 | 0.01 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.