Best TWAS P=3.467365e-12 · Best GWAS P=0.008629081 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL | Epha6 | alternative TSS | ENSRNOT00000047310 | 0.03 | 0.03 | enet | 548 | 0.03 | 0.0034 | -1.7 | -6.4 | 1.8e-10 | 1.00 | 0.15 | 0.09 | FALSE |
| 2 | PL | Epha6 | alternative TSS | ENSRNOT00000097751 | 0.04 | 0.03 | enet | 379 | 0.03 | 0.0012 | -1.7 | 7.0 | 3.5e-12 | -0.99 | 0.16 | 0.10 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.