Best TWAS P=2.729157e-15 · Best GWAS P=0.007901267 conditioned to 0.001003853
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Liver | RGD1566134 | intron excision ratio | chr5:75204357:75224619 | 0.83 | 0.01 | enet | 37 | 0.31 | 9.3e-35 | 1.8 | 7.9 | 2.7e-15 | -0.08 | 0.09 | 0.08 | TRUE |
| 2 | Liver | RGD1566134 | intron excision ratio | chr5:75224310:75224619 | 0.84 | 0.07 | enet | 33 | 0.24 | 3.1e-26 | 1.8 | -5.7 | 1.5e-08 | 0.45 | 0.09 | 0.09 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.