Best TWAS P=9.419026e-08 · Best GWAS P=4.632023e-07 conditioned to 0.7255398
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Slx4 | mRNA stability | ENSRNOG00000024445 | 0.36 | 0.36 | blup | 1649 | 0.37 | 2.3e-43 | -4.5 | 5.1 | 3.4e-07 | -0.89 | 0.52 | 0.48 | FALSE |
| 2 | PL | Slx4 | mRNA stability | ENSRNOG00000024445 | 0.18 | 0.15 | blup | 1646 | 0.15 | 1.2e-11 | -4.6 | 5.3 | 9.4e-08 | -0.92 | 0.20 | 0.80 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.