Best TWAS P=1.50e-09 · Best GWAS P=9.06e-10 conditioned to 9.07e-02
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Tenm4 | alternative TSS | XM_039113170.1 | 0.08 | 3248 | 0.02 | 5.9e-03 | 5.84 | 5.17e-09 | 0.3 | FALSE |
| Adipose | Tenm4 | isoform ratio | XM_039113176.1 | 0.08 | 1 | 0.04 | 2.4e-05 | -5.95 | 2.68e-09 | 0.44 | FALSE |
| Adipose | Tenm4 | intron excision ratio | chr1_150726222_150781008 | 0.1 | 3248 | 0.06 | 3.7e-07 | 5.32 | 1.05e-07 | 0.63 | FALSE |
| BLA | Tenm4 | intron excision ratio | chr1_150700925_150781008 | 0.11 | 3248 | 0.08 | 4.8e-05 | -5.62 | 1.94e-08 | 0.61 | FALSE |
| Brain | Tenm4 | intron excision ratio | chr1_151150960_151158532 | 0.06 | 1 | 0 | 1.2e-01 | -5.44 | 5.37e-08 | 0.03 | FALSE |
| NAcc | Tenm4 | gene expression | Tenm4 | 0.05 | 3248 | 0.02 | 7.5e-04 | -6.04 | 1.50e-09 | 0.57 | TRUE |
| NAcc | Tenm4 | isoform ratio | XM_017589181.2 | 0.03 | 3248 | 0.01 | 5.7e-03 | -5.43 | 5.60e-08 | 0.29 | FALSE |
| NAcc | Tenm4 | intron excision ratio | chr1_150700925_150781008 | 0.17 | 1 | 0.08 | 5.1e-10 | 5.44 | 5.47e-08 | 0.23 | FALSE |
| PL | Tenm4 | intron excision ratio | chr1_150700925_150781008 | 0.04 | 3248 | 0.02 | 3.3e-03 | -5.18 | 2.21e-07 | 0.27 | FALSE |
| PL | Tenm4 | intron excision ratio | chr1_150845205_150898763 | 0.06 | 1 | 0.04 | 3.3e-05 | 5.84 | 5.19e-09 | 0.39 | FALSE |