Best TWAS P=3.203533e-07 · Best GWAS P=6.270178e-08 conditioned to 0.0212304
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL | Eea1 | isoform ratio | ENSRNOT00000117665 | 0.26 | 0.33 | lasso | 20 | 0.34 | 1.4e-26 | 4.6 | 5.1 | 3.2e-07 | -0.77 | 0.35 | 0.65 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.