Best TWAS P=1.554757e-07 · Best GWAS P=2.342217e-05 conditioned to 0.1566929
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Unc13a | alternative TSS | ENSRNOT00000103348 | 0.57 | 0 | enet | 176 | 0.03 | 0.00065 | -3.9 | -5.2 | 1.6e-07 | -0.59 | 0.13 | 0.15 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.