Best TWAS P=1.084731e-07 · Best GWAS P=7.600815e-09 conditioned to 0.006031388
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | NAcc | Erc2 | gene expression | ENSRNOG00000015148 | 0.29 | 0.16 | lasso | 13 | 0.17 | 1.2e-12 | 5.5 | -5.3 | 1.1e-07 | 0.74 | 0.36 | 0.64 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.