Best TWAS P=1.284068e-08 · Best GWAS P=9.111356e-07 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Apc | intron excision ratio | chr18:25864409:25871423 | 0.07 | 0.02 | blup | 1199 | 0.02 | 7.0e-03 | 4.8 | 5.2 | 1.6e-07 | 0.94 | 0.30 | 0.54 | FALSE |
| 2 | Liver | Srp19 | gene expression | ENSRNOG00000020204 | 0.04 | 0.02 | blup | 1227 | 0.02 | 3.9e-03 | 3.4 | 5.5 | 3.0e-08 | 0.94 | 0.36 | 0.54 | FALSE |
| 3 | Liver | Fam13b | gene expression | ENSRNOG00000020384 | 0.14 | 0.11 | blup | 1001 | 0.13 | 2.8e-14 | 3.4 | 5.4 | 7.7e-08 | 0.95 | 0.39 | 0.61 | FALSE |
| 4 | NAcc | Reep5 | gene expression | ENSRNOG00000020167 | 0.41 | 0.13 | blup | 1159 | 0.13 | 6.6e-04 | 4.9 | 5.7 | 1.3e-08 | 0.95 | 0.32 | 0.54 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.