Best TWAS P=7.773885e-17 · Best GWAS P=0.03062974 conditioned to 2.08507e-10
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Liver | Ccs | gene expression | ENSRNOG00000047816 | 0.07 | 0.05 | enet | 10 | 0.06 | 5.1e-07 | -0.12 | 8.3 | 7.8e-17 | -0.43 | 0.04 | 0.02 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.