Best TWAS P=3.405405e-07 · Best GWAS P=0.01063343 conditioned to 0.09615798
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | Slc12a7 | alternative TSS | ENSRNOT00000078039 | 0.03 | 0.02 | enet | 203 | 0.02 | 0.0095 | 2.1 | -5.1 | 3.4e-07 | -0.18 | 0.02 | 0.08 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.