Best TWAS P=2.919914e-09 · Best GWAS P=0.1420146 conditioned to 1.907284e-15
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Vit | mRNA stability | ENSRNOG00000004706 | 0.05 | 0.02 | enet | 101 | 0.03 | 0.00017 | 1.2 | 5.9 | 2.9e-09 | -0.7 | 0.04 | 0.04 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.