Best TWAS P=2.014643e-15 · Best GWAS P=0.068205 conditioned to 2.609805e-16
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | BLA | Syt5 | mRNA stability | ENSRNOG00000018217 | 0.06 | 0 | enet | 782 | 0.01 | 0.16 | 0.16 | -7.9 | 2e-15 | 0.6 | 0.04 | 0.02 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.