Best TWAS P=8.765815e-08 · Best GWAS P=5.22232e-08 conditioned to 1
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | BLA | Gabrb2 | gene expression | ENSRNOG00000003680 | 0.13 | 0.06 | top1 | 1 | 0.06 | 5.5e-04 | 5.2 | 5.2 | 2.2e-07 | 0.92 | 0.07 | 0.24 | FALSE |
| 2 | Brain | Gabrg2 | mRNA stability | ENSRNOG00000003241 | 0.50 | 0.50 | blup | 1795 | 0.52 | 2.8e-55 | 5.4 | 5.4 | 8.8e-08 | 0.99 | 0.48 | 0.52 | TRUE |
| 3 | IL | Gabrg2 | mRNA stability | ENSRNOG00000003241 | 0.23 | 0.22 | top1 | 1 | 0.22 | 6.8e-06 | 5.2 | 5.2 | 1.8e-07 | 0.99 | 0.24 | 0.22 | FALSE |
| 4 | NAcc | Gabrg2 | mRNA stability | ENSRNOG00000003241 | 0.25 | 0.21 | lasso | 38 | 0.23 | 6.8e-17 | 5.2 | 5.2 | 1.9e-07 | 1.00 | 0.47 | 0.53 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.