Best TWAS P=9.290717e-08 · Best GWAS P=0.04086669 conditioned to 3.222069e-16
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | IL | Matn2 | isoform ratio | ENSRNOT00000100118 | 0.13 | 0.05 | enet | 65 | 0.12 | 0.001 | 1.8 | 5.3 | 9.3e-08 | -0.7 | 0.04 | 0.02 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.