chr20:8,909-796,244

Trait: Epididymis fat weight

Best TWAS P = 1.91e-09 · Best GWAS P= 1.42e-07 conditioned to 1.00e+00

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Tmlhe gene expression Tmlhe 0.33 18 0.21 1.2e-22 5.55 2.82e-08 0.68 FALSE
BLA Tmlhe intron excision ratio chr20_107697_113298 0.37 24 0.09 1.3e-05 5.22 1.78e-07 0.66 TRUE
Brain Tmlhe alternative TSS NM_133387.2 0.08 35 0.08 1.2e-07 5.7 1.21e-08 0.22 TRUE
Brain Tmlhe alternative TSS XM_006255855.3 0.03 21 0.03 5.4e-04 -5.35 9.00e-08 0.27 FALSE
Brain Tmlhe alternative TSS NM_133387.2 0.03 1 0.04 2.7e-04 5.63 1.77e-08 0.63 FALSE
Brain Tmlhe alternative TSS XM_006255855.3 0.03 6 0.04 2.4e-04 -5.6 2.15e-08 0.35 FALSE
Brain LOC120098879 gene expression LOC120098879 0.65 42 0.62 6.5e-74 -5.65 1.57e-08 0.16 TRUE
Brain Tmlhe isoform ratio XM_006255855.3 0.43 2589 0.29 1.4e-27 5.44 5.37e-08 0.67 FALSE
Brain Tmlhe intron excision ratio chr20_107697_113298 0.17 2589 0.13 3.5e-12 5.36 8.19e-08 0.67 FALSE
IC Tmlhe intron excision ratio chr20_107697_113298 0.18 2589 0.06 1.8e-03 5.81 6.35e-09 0.61 FALSE
IC Tmlhe intron excision ratio chr20_111063_113298 0.09 2589 0.01 8.5e-02 -5.42 5.96e-08 0.21 FALSE
IL LOC120098879 isoform ratio XM_063279601.1 0.2 1 0.07 1.1e-02 5.53 3.15e-08 0.14 FALSE
IL LOC120098879 isoform ratio XM_063279602.1 0.2 1 0.06 1.2e-02 -5.53 3.15e-08 0.14 TRUE
NAcc Tmlhe isoform ratio XM_006255855.3 0.41 2589 0.18 2.7e-26 6 1.91e-09 0.67 TRUE
NAcc Tmlhe intron excision ratio chr20_107697_113298 0.16 36 0.11 7.4e-17 5.74 9.61e-09 0.67 FALSE
NAcc Tmlhe intron excision ratio chr20_111063_113298 0.07 2589 0.06 3.0e-09 -5.98 2.29e-09 0.22 FALSE
PL Tmlhe isoform ratio XM_006255855.3 0.2 2589 0.15 9.9e-16 5.31 1.08e-07 0.67 FALSE
PL Tmlhe intron excision ratio chr20_107697_113298 0.09 2589 0.07 6.3e-08 5.9 3.70e-09 0.66 FALSE
pVTA Tmlhe gene expression Tmlhe 0.16 2589 0.03 9.6e-04 5.69 1.30e-08 0.23 TRUE
pVTA Tmlhe isoform ratio XM_006255855.3 0.17 36 0.12 7.4e-10 5.26 1.44e-07 0.67 FALSE
pVTA Tmlhe intron excision ratio chr20_107697_113298 0.18 2589 0.16 7.8e-13 5.56 2.74e-08 0.67 FALSE
pVTA LOC120098879 mRNA stability LOC120098879 0.04 2560 0.04 6.5e-04 -5.3 1.18e-07 0.24 FALSE