Hub : Traits : Epididymis fat weight : ←

chr20:4,913,192-6,657,065

Trait: Epididymis fat weight

Best TWAS P=7.681374e-10 · Best GWAS P=1.862341e-09 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	NA	alternative polyA	ENSRNOT00000090993	0.06	0.02	lasso	11	0.03	5.0e-04	-5.9	-5.5	3.2e-08	-0.92	0.11	0.85	FALSE
2	Adipose	NA	alternative polyA	ENSRNOT00000115941	0.08	0.03	lasso	13	0.04	6.6e-05	-5.6	5.5	3.3e-08	0.81	0.10	0.90	FALSE
3	Adipose	Spdef	gene expression	ENSRNOG00000000491	0.11	0.05	top1	1	0.05	7.4e-06	-5.9	5.9	3.1e-09	-0.61	0.08	0.73	TRUE
4	Adipose	Snrpc	gene expression	ENSRNOG00000000493	0.70	0.06	enet	230	0.26	3.5e-28	-4.9	-5.3	1.1e-07	0.71	0.17	0.83	FALSE
5	Adipose	Ilrun	gene expression	ENSRNOG00000038883	0.72	0.42	enet	101	0.52	9.1e-68	-5.9	6.0	2.4e-09	-0.92	0.15	0.85	FALSE
6	Adipose	NA	gene expression	ENSRNOG00000058912	0.72	0.28	enet	61	0.49	1.9e-61	-5.6	6.0	2.5e-09	-0.87	0.09	0.91	FALSE
7	BLA	Nudt3	gene expression	ENSRNOG00000061176	0.25	0.11	top1	1	0.11	2.0e-06	-5.5	-5.5	3.2e-08	0.76	0.35	0.39	FALSE
8	Eye	Ilrun	gene expression	ENSRNOG00000038883	0.91	0.20	blup	2269	0.29	2.2e-05	-4.9	5.4	6.4e-08	-0.84	0.21	0.68	FALSE
9	IL	NA	gene expression	ENSRNOG00000058912	0.33	0.12	top1	1	0.12	9.2e-04	-5.5	5.5	3.1e-08	-0.89	0.12	0.06	FALSE
10	IL	Nudt3	gene expression	ENSRNOG00000061176	0.31	0.01	enet	112	0.12	7.5e-04	-3.7	-6.1	1.3e-09	0.60	0.50	0.19	FALSE
11	IL	Taf11	mRNA stability	ENSRNOG00000024601	0.49	0.21	blup	2286	0.26	6.6e-07	-4.2	5.9	4.6e-09	-0.77	0.82	0.16	FALSE
12	LHb	Ilrun	gene expression	ENSRNOG00000038883	0.75	0.14	blup	2267	0.16	1.2e-04	-4.9	5.4	8.1e-08	-0.94	0.11	0.88	FALSE
13	Liver	Hmga1	gene expression	ENSRNOG00000000488	0.09	0.00	blup	2507	0.01	6.9e-02	-4.9	-5.7	1.2e-08	0.72	0.16	0.65	FALSE
14	Liver	Snrpc	gene expression	ENSRNOG00000000493	0.90	0.25	enet	147	0.48	1.8e-59	-5.9	-6.2	7.7e-10	0.92	0.15	0.85	TRUE
15	Liver	Taf11	gene expression	ENSRNOG00000024601	0.09	0.02	enet	58	0.03	5.0e-04	-3.4	-6.1	9.8e-10	0.38	0.67	0.23	TRUE
16	Liver	Ilrun	gene expression	ENSRNOG00000038883	0.87	0.40	enet	68	0.41	7.0e-49	-5.9	5.3	1.2e-07	-0.99	0.15	0.85	FALSE
17	Liver	Nudt3	gene expression	ENSRNOG00000061176	0.11	0.00	enet	44	0.03	1.8e-04	-5.4	-5.6	2.3e-08	0.74	0.32	0.53	TRUE
18	Liver	Snrpc	intron excision ratio	chr20:5896204:5896392	0.54	0.20	enet	164	0.39	2.2e-45	-3.3	-5.4	6.1e-08	0.79	0.56	0.44	FALSE
19	NAcc	Ilrun	gene expression	ENSRNOG00000038883	0.82	0.49	blup	2268	0.62	4.6e-58	-5.9	5.5	4.7e-08	-0.96	0.08	0.92	FALSE
20	NAcc	NA	gene expression	ENSRNOG00000058912	0.21	0.11	top1	1	0.11	2.2e-08	-5.9	5.9	3.2e-09	-0.60	0.09	0.91	TRUE
21	OFC	Uhrf1bp1	isoform ratio	ENSRNOT00000102198	0.20	-0.01	blup	2284	0.04	4.3e-02	-5.5	5.3	8.8e-08	-0.78	0.39	0.43	FALSE
22	OFC	Ilrun	intron excision ratio	chr20:5812549:5825543	0.52	0.17	top1	1	0.17	7.9e-05	-5.5	-5.5	3.1e-08	0.63	0.12	0.07	FALSE
23	PL	Pacsin1	gene expression	ENSRNOG00000054603	0.13	0.09	enet	34	0.12	1.3e-09	-4.1	5.1	3.3e-07	-0.70	0.91	0.09	FALSE
24	PL	NA	gene expression	ENSRNOG00000058912	0.37	0.16	blup	2282	0.17	1.2e-12	-5.9	5.5	4.4e-08	-0.96	0.08	0.92	FALSE
25	PL	Nudt3	gene expression	ENSRNOG00000061176	0.22	0.10	top1	1	0.10	2.6e-08	-5.5	-5.5	3.4e-08	0.80	0.48	0.52	TRUE
26	PL	Ilrun	intron excision ratio	chr20:5812549:5825543	0.09	0.01	blup	2268	0.04	5.1e-04	-5.5	-5.9	3.2e-09	0.81	0.51	0.39	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.