chr9:12,862,716-16,264,314

Trait: BMI without tail

Best TWAS P=1.44e-09 · Best GWAS P=1.44e-09 conditioned to 2.20e-01

Associated models

Tissue Gene RNA modality RNA phenotype h2 # weights Model R2 Model R2 P TWAS Z TWAS P Coloc P Joint
Adipose Aars2 gene expression Aars2 0.23 1 0.16 4.8e-17 5.8 6.48e-09 0.66 FALSE
Adipose Cdc5l gene expression Cdc5l 0.07 2000 0.07 4.1e-08 -5.66 1.51e-08 0.73 FALSE
Adipose Klc4 gene expression Klc4 0.05 1222 0.04 2.3e-05 5.34 9.10e-08 0.58 FALSE
Adipose Mrpl2 gene expression Mrpl2 0.05 1222 0.01 4.7e-02 -5.19 2.16e-07 0.32 FALSE
Adipose Ptk7 gene expression Ptk7 0.19 1192 0.18 1.2e-19 5.39 7.18e-08 0.63 FALSE
Adipose Rrp36 gene expression Rrp36 0.44 1253 0.45 2.5e-55 5.3 1.16e-07 0.64 FALSE
Adipose Slc29a1 gene expression Slc29a1 0.18 17 0.13 5.4e-14 -5.8 6.65e-09 0.72 FALSE
BLA Aars2 alternative TSS XM_006244515.4 0.11 1991 0.07 1.9e-04 5.27 1.34e-07 0.37 FALSE
BLA Mea1 alternative TSS XM_008766880.2 0.06 1 0.04 2.0e-03 5.26 1.42e-07 0.05 FALSE
BLA Klc4 gene expression Klc4 0.14 17 0.16 8.1e-09 5.26 1.42e-07 0.64 FALSE
BLA LOC681367 gene expression LOC681367 0.18 122 0.21 2.5e-11 -5.43 5.57e-08 0.6 FALSE
BLA Mrps10 gene expression Mrps10 0.47 1746 0.39 4.3e-22 5.4 6.78e-08 0.65 FALSE
BLA Rrp36 gene expression Rrp36 0.42 105 0.51 5.6e-31 -5.2 2.00e-07 0.62 FALSE
BLA Klc4 isoform ratio XM_006244516.4 0.06 1222 0.01 6.2e-02 -5.35 8.85e-08 0.39 FALSE
BLA Trerf1 intron excision ratio chr9_13710850_13768409 0.13 1 0.11 1.5e-06 -5.34 9.33e-08 0.49 FALSE
BLA Rrp36 mRNA stability Rrp36 0.12 18 0.12 7.3e-07 5.26 1.48e-07 0.56 FALSE
BLA Trerf1 mRNA stability Trerf1 0.11 54 0.1 3.7e-06 -5.56 2.65e-08 0.38 FALSE
Brain Slc29a1 alternative TSS XM_006244561.3 0.04 1 0.03 3.4e-04 -5.28 1.27e-07 0.03 FALSE
Brain Slc29a1 alternative TSS XM_006244561.3 0.04 1 0.04 2.7e-04 -5.77 7.85e-09 0.08 FALSE
Brain C9h6orf132 gene expression C9h6orf132 0.06 1 0.05 2.0e-05 -5.26 1.44e-07 0.73 FALSE
Brain Hsp90ab1 gene expression Hsp90ab1 0.11 10 0.11 2.8e-10 -5.35 8.74e-08 0.57 FALSE
Brain Klc4 gene expression Klc4 0.75 79 0.67 9.2e-83 -5.19 2.14e-07 0.62 FALSE
Brain Mrpl2 gene expression Mrpl2 0.05 1 0.03 1.5e-03 5.34 9.27e-08 0.07 FALSE
Brain Rrp36 gene expression Rrp36 0.6 56 0.55 3.0e-60 5.17 2.28e-07 0.61 FALSE
Brain Spats1 gene expression Spats1 0.44 31 0.34 1.6e-32 5.24 1.62e-07 0 FALSE
Brain Srf gene expression Srf 0.04 1042 0.01 3.2e-02 5.27 1.38e-07 0.57 FALSE
Brain Klc4 isoform ratio XM_039083506.1 0.07 5 0.05 3.6e-05 5.51 3.67e-08 0.57 FALSE
Brain Klhdc3 isoform ratio XM_039083821.1 0.08 167 0.06 2.6e-06 5.36 8.55e-08 0.63 FALSE
Brain Klhdc3 intron excision ratio chr9_14302484_14303967 0.15 1 0.14 1.5e-12 5.34 9.27e-08 0.78 FALSE
Brain Klhdc3 intron excision ratio chr9_14304118_14304654 0.11 1280 0.11 9.0e-11 -5.41 6.21e-08 0.6 FALSE
Brain Trerf1 intron excision ratio chr9_13768495_13856943 0.05 1 0.05 8.2e-06 -5.23 1.70e-07 0.35 FALSE
Brain Cul7 mRNA stability Cul7 0.15 23 0.17 1.4e-15 5.38 7.64e-08 0.59 FALSE
Brain Trerf1 mRNA stability Trerf1 0.13 27 0.15 5.8e-14 -5.24 1.59e-07 0.39 FALSE
Eye Zfp318 alternative polyA XM_039084821.1 0.27 1 0.14 4.1e-03 -5.33 1.00e-07 0.06 FALSE
IL Trerf1 alternative polyA XM_039083502.1 0.16 1 0.07 1.0e-02 -5.32 1.02e-07 0.05 FALSE
IL Nfkbie gene expression Nfkbie 0.24 2030 0.09 3.7e-03 -5.67 1.42e-08 0.54 FALSE
IL Klhdc3 isoform ratio NM_001012203.1 0.33 220 0.31 4.0e-08 5.9 3.56e-09 0.6 FALSE
IL Klhdc3 intron excision ratio chr9_14302484_14304654 0.29 46 0.25 1.0e-06 -5.37 7.85e-08 0.59 FALSE
IL Klhdc3 intron excision ratio chr9_14304118_14304654 0.15 10 0.11 1.7e-03 5.75 8.95e-09 0.35 FALSE
IL Klhdc3 mRNA stability Klhdc3 0.14 1280 0.08 5.5e-03 5.22 1.84e-07 0.3 FALSE
LHb C9h6orf132 gene expression C9h6orf132 0.2 1 0.08 6.7e-03 -5.3 1.19e-07 0.08 FALSE
LHb Klhdc3 isoform ratio NM_001012203.1 0.26 46 0.11 1.6e-03 5.27 1.36e-07 0.48 FALSE
LHb Klhdc3 isoform ratio XM_006244542.4 0.24 16 0.08 5.5e-03 -5.29 1.26e-07 0.44 FALSE
Liver Capn11 alternative polyA XM_039084033.1 0.03 1897 0.01 1.3e-02 5.46 4.65e-08 0.63 FALSE
Liver Slc29a1 alternative TSS NM_031684.2 0.13 1 0.14 8.6e-15 5.98 2.22e-09 0.84 FALSE
Liver Slc29a1 alternative TSS XM_006244561.3 0.04 2002 0.02 3.8e-03 5.3 1.16e-07 0.26 FALSE
Liver Slc29a1 alternative TSS XM_039084162.1 0.08 1 0.08 7.5e-09 -5.98 2.22e-09 0.84 FALSE
Liver Slc29a1 alternative TSS XM_006244561.3 0.04 2002 0.02 2.7e-03 5.29 1.26e-07 0.26 FALSE
Liver Aars2 gene expression Aars2 0.23 17 0.21 2.6e-23 -5.88 4.04e-09 0.74 FALSE
Liver Capn11 gene expression Capn11 0.26 29 0.25 7.3e-28 -5.93 2.96e-09 0.74 FALSE
Liver Gnmt gene expression Gnmt 0.36 1351 0.32 1.5e-36 5.33 9.82e-08 0.62 FALSE
Liver Hsp90ab1 gene expression Hsp90ab1 0.03 2017 0.02 2.3e-03 -5.8 6.58e-09 0.67 FALSE
Liver LOC103690501 gene expression LOC103690501 0.16 1697 0.19 2.8e-20 5.48 4.35e-08 0.73 FALSE
Liver Rrp36 gene expression Rrp36 0.42 1253 0.42 4.0e-50 5.2 2.00e-07 0.64 FALSE
Liver Slc29a1 gene expression Slc29a1 0.07 1 0.06 1.5e-07 -5.49 3.92e-08 0.24 FALSE
Liver Slc35b2 gene expression Slc35b2 0.03 2024 0.02 2.1e-03 -5.97 2.32e-09 0.65 FALSE
Liver Zfp318 gene expression Zfp318 0.16 1073 0.03 1.1e-04 -5.31 1.07e-07 0.34 FALSE
Liver Klhdc3 isoform ratio NM_001012203.1 0.14 1280 0.17 1.6e-18 -5.25 1.49e-07 0.63 FALSE
Liver Klhdc3 isoform ratio XM_006244542.4 0.14 1280 0.16 7.6e-18 5.35 9.03e-08 0.62 FALSE
Liver Slc29a1 isoform ratio NM_031684.2 0.18 17 0.18 2.9e-19 -5.88 4.04e-09 0.77 FALSE
Liver Slc29a1 isoform ratio XM_006244560.3 0.04 15 0.04 5.7e-05 5.38 7.31e-08 0.68 FALSE
Liver Slc29a1 isoform ratio XM_039084162.1 0.05 1 0.04 2.2e-05 -5.49 3.92e-08 0.13 FALSE
Liver Cnpy3 intron excision ratio chr9_14242382_14245813 0.03 1411 0.02 5.6e-03 -5.4 6.79e-08 0.44 FALSE
Liver Slc29a1 intron excision ratio chr9_15399733_15405034 0.19 27 0.2 3.1e-21 -5.85 4.83e-09 0.76 FALSE
Liver Slc29a1 intron excision ratio chr9_15403262_15405034 0.12 1 0.14 1.2e-15 -5.49 3.92e-08 0.25 FALSE
Liver Pex6 mRNA stability Pex6 0.14 1332 0.11 4.2e-12 -5.22 1.76e-07 0.62 FALSE
NAcc Nfkbie gene expression Nfkbie 0.04 18 0.02 2.5e-03 5.33 9.65e-08 0.44 FALSE
NAcc Rrp36 gene expression Rrp36 0.34 43 0.55 1.5e-75 5.23 1.67e-07 0.64 FALSE
NAcc Trerf1 isoform ratio XM_006244452.4 0.02 1886 0.01 1.1e-02 5.26 1.45e-07 0.4 FALSE
NAcc Trerf1 intron excision ratio chr9_13710850_13768409 0.09 1886 0.08 2.1e-09 5.42 5.91e-08 0.58 FALSE
NAcc Trerf1 intron excision ratio chr9_13760250_13761689 0.06 1 0.09 9.6e-11 5.24 1.65e-07 0.63 FALSE
NAcc Trerf1 intron excision ratio chr9_13761791_13768409 0.03 1 0.02 2.0e-03 5.3 1.19e-07 0.16 FALSE
NAcc Ppp2r5d mRNA stability Ppp2r5d 0.03 19 0.01 7.6e-03 5.25 1.56e-07 0.29 FALSE
NAcc Rrp36 mRNA stability Rrp36 0.03 1 0.04 2.1e-05 -5.26 1.45e-07 0.44 FALSE
NAcc Trerf1 mRNA stability Trerf1 0.17 4 0.15 6.9e-17 5.21 1.89e-07 0.09 FALSE
NAcc Ubr2 mRNA stability Ubr2 0.02 1700 0.02 9.5e-04 5.19 2.07e-07 0.52 FALSE
OFC Bicral alternative TSS NM_001106888.1 0.2 1711 0.07 8.9e-03 5.19 2.14e-07 0.25 FALSE
OFC Bicral alternative TSS XM_006244508.4 0.2 1711 0.1 1.9e-03 -5.21 1.85e-07 0.27 FALSE
OFC Pex6 gene expression Pex6 0.57 16 0.4 1.0e-10 -5.24 1.60e-07 0.6 FALSE
PL Aars2 alternative polyA NM_001106891.1 0.04 1 0.04 9.6e-05 -5.49 3.92e-08 0.08 FALSE
PL Aars2 alternative polyA XM_006244513.4 0.05 16 0.03 3.5e-04 -5.69 1.25e-08 0.68 FALSE
PL Aars2 alternative TSS XM_006244515.4 0.12 1991 0.1 4.8e-11 5.18 2.22e-07 0.01 FALSE
PL Klhdc3 alternative TSS NM_001012203.1 0.03 1280 0.03 1.7e-04 -5.18 2.27e-07 0.37 FALSE
PL Cul7 gene expression Cul7 0.16 27 0.18 4.2e-19 5.32 1.02e-07 0.62 FALSE
PL Hsp90ab1 gene expression Hsp90ab1 0.07 26 0.07 2.2e-08 -6.03 1.61e-09 0.77 FALSE
PL Nfkbie gene expression Nfkbie 0.06 2030 0.04 1.1e-05 -5.73 1.03e-08 0.63 FALSE
PL Rrp36 gene expression Rrp36 0.49 41 0.61 3.4e-84 5.27 1.39e-07 0.63 FALSE
PL Slc35b2 gene expression Slc35b2 0.04 2025 0.01 3.8e-02 -5.65 1.58e-08 0.57 FALSE
PL Spats1 gene expression Spats1 0.09 1 0.07 2.7e-08 -5.49 3.92e-08 0.25 FALSE
PL Trerf1 intron excision ratio chr9_13760250_13761689 0.07 1 0.1 2.6e-11 5.26 1.43e-07 0.66 FALSE
PL Vegfa intron excision ratio chr9_14956379_14959271 0.03 1 0.01 1.6e-02 5.28 1.30e-07 0.03 FALSE
PL Cul7 mRNA stability Cul7 0.02 1229 0.02 3.9e-03 -5.37 7.82e-08 0.57 FALSE
PL Rrp36 mRNA stability Rrp36 0.04 13 0.05 5.5e-06 -5.24 1.60e-07 0.6 FALSE
PL Trerf1 mRNA stability Trerf1 0.14 23 0.17 1.1e-18 5.48 4.21e-08 0.57 FALSE
pVTA LOC681367 gene expression LOC681367 0.12 1517 0.08 1.8e-04 5.44 5.42e-08 0.57 FALSE
pVTA Nfkbie gene expression Nfkbie 0.12 23 0.1 6.5e-05 -5.29 1.20e-07 0.66 FALSE
pVTA Spats1 gene expression Spats1 0.12 2005 0.06 1.1e-03 5.36 8.20e-08 0.67 FALSE
pVTA Tcte1 gene expression Tcte1 0.09 1 0.06 2.0e-03 -6.05 1.44e-09 0.1 TRUE
pVTA Klhdc3 isoform ratio NM_001012203.1 0.32 32 0.38 1.8e-17 5.47 4.40e-08 0.6 FALSE
pVTA Klhdc3 isoform ratio XM_006244542.4 0.39 1280 0.41 5.5e-19 5.19 2.08e-07 0.6 FALSE
pVTA Trerf1 isoform ratio XM_039083496.1 0.09 1886 0.02 3.2e-02 -5.47 4.40e-08 0.32 FALSE
RMTg Cnpy3 gene expression Cnpy3 0.51 1 0.35 4.5e-10 5.19 2.06e-07 0.57 FALSE
RMTg LOC681367 gene expression LOC681367 0.14 1517 0.08 3.9e-03 5.44 5.42e-08 0.42 FALSE
RMTg Rrp36 gene expression Rrp36 0.58 47 0.18 1.8e-05 5.2 1.99e-07 0.59 FALSE