Best TWAS P=2.313643e-07 · Best GWAS P=1.018774e-05 conditioned to 0.6617668
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | PCOLCE2 | gene expression | ENSRNOG00000046848 | 0.16 | 0.11 | blup | 2007 | 0.13 | 9.1e-12 | -3.8 | 5.2 | 2.3e-07 | -0.8 | 0.24 | 0.68 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.