Best TWAS P = 4.64e-08 · Best GWAS P= 7.30e-08 conditioned to 1.00e+00
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Brain | Rpe | intron excision ratio | chr9_75647106_75651469 | 0.06 | 26 | 0.06 | 6.3e-06 | -5.46 | 4.64e-08 | 0.67 | TRUE |
| Brain | Rpe | intron excision ratio | chr9_75647106_75656762 | 0.08 | 1 | 0.08 | 3.3e-08 | 5.25 | 1.50e-07 | 0.89 | FALSE |
| Brain | Rpe | intron excision ratio | chr9_75651561_75656762 | 0.04 | 1 | 0.03 | 3.9e-04 | -5.25 | 1.50e-07 | 0.2 | FALSE |
| Liver | Rpe | gene expression | Rpe | 0.16 | 1 | 0.1 | 6.8e-11 | 5.27 | 1.33e-07 | 0.91 | FALSE |