Best TWAS P=1.354764e-07 · Best GWAS P=7.376863e-07 conditioned to 1
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | PL | Ndfip1 | alternative TSS | ENSRNOT00000096236 | 0.12 | 0.03 | enet | 122 | 0.04 | 0.00058 | 4.7 | 5.3 | 1.4e-07 | 0.95 | 0.08 | 0.84 | TRUE |
2 | PL | Ndfip1 | alternative TSS | ENSRNOT00000096236 | 0.12 | 0.01 | enet | 58 | 0.03 | 0.00140 | 4.7 | 5.2 | 1.6e-07 | 0.97 | 0.15 | 0.69 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.