Best TWAS P=1.421458e-07 · Best GWAS P=9.119903e-08 conditioned to 0.01064713
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | BLA | Axin2 | gene expression | ENSRNOG00000055010 | 0.07 | 0.08 | top1 | 1 | 0.08 | 4.9e-05 | 5.1 | 5.1 | 2.9e-07 | 0.96 | 0.11 | 0.14 | FALSE |
| 2 | Brain | Cep112 | gene expression | ENSRNOG00000024557 | 0.11 | 0.09 | enet | 4 | 0.10 | 1.3e-09 | 5.1 | 5.3 | 1.4e-07 | -0.60 | 0.31 | 0.69 | TRUE |
| 3 | PL | Cep112 | gene expression | ENSRNOG00000024557 | 0.20 | 0.06 | top1 | 1 | 0.06 | 1.8e-02 | 5.2 | 5.2 | 2.2e-07 | 0.91 | 0.11 | 0.06 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.