Best TWAS P=2.271696e-08 · Best GWAS P=6.725031e-05 conditioned to 0.003061251
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Liver | Rap2b | gene expression | ENSRNOG00000065432 | 0.03 | 0.02 | enet | 13 | 0.03 | 0.00085 | 3.8 | 5.6 | 2.3e-08 | 0.19 | 0.59 | 0.34 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.