Hub : Traits : tb_th_sd : ← →

chr2:147,028,669-150,452,756

Best TWAS P=2.045018e-08 · Best GWAS P=2.474019e-08 conditioned to 1

Associated models

#	Tissue	Gene	Modality	RNA phenotype	h2	eQTL R2	model	# weights	model R2	model R2 P	eQTL GWAS Z	TWAS Z	TWAS P	Top SNP corr	PP3	PP4	joint
1	Adipose	Ssr3	gene expression	ENSRNOG00000011148	0.08	0.05	top1	1	0.05	6.0e-06	5.5	-5.5	2.9e-08	-0.88	0.20	0.68	FALSE
2	Adipose	Kcnab1	gene expression	ENSRNOG00000056697	0.34	0.04	top1	1	0.04	4.4e-05	5.3	5.3	1.2e-07	0.76	0.15	0.37	FALSE
3	Adipose	NA	gene expression	ENSRNOG00000065468	0.16	0.10	top1	1	0.10	1.0e-10	5.3	-5.3	1.5e-07	-0.88	0.56	0.44	FALSE
4	BLA	Ssr3	gene expression	ENSRNOG00000011148	0.77	0.67	enet	184	0.70	4.7e-51	5.3	-5.1	2.9e-07	-0.96	0.48	0.52	FALSE
5	BLA	Gmps	isoform ratio	ENSRNOT00000076292	0.12	0.04	enet	122	0.05	1.6e-03	5.1	5.4	5.5e-08	0.94	0.40	0.45	FALSE
6	BLA	Gmps	isoform ratio	ENSRNOT00000084238	0.22	0.07	enet	137	0.08	5.8e-05	5.1	-5.6	2.0e-08	-0.95	0.47	0.52	TRUE
7	BLA	Ssr3	mRNA stability	ENSRNOG00000011148	0.12	0.06	top1	1	0.06	5.1e-04	5.4	-5.4	8.5e-08	-0.91	0.09	0.06	FALSE
8	BLA	Kcnab1	mRNA stability	ENSRNOG00000056697	0.82	0.42	top1	1	0.42	3.6e-24	5.3	-5.3	1.2e-07	-0.76	0.27	0.73	FALSE
9	Brain	Gmps	alternative TSS	ENSRNOT00000076880	0.13	0.08	blup	862	0.09	5.8e-09	5.1	5.4	8.3e-08	0.87	0.45	0.55	FALSE
10	Brain	Gmps	alternative TSS	ENSRNOT00000076880	0.13	0.09	lasso	35	0.11	4.7e-10	5.1	5.4	7.0e-08	0.87	0.46	0.54	FALSE
11	Brain	Gmps	alternative TSS	ENSRNOT00000084238	0.13	0.09	lasso	37	0.11	5.6e-10	5.1	-5.4	6.6e-08	-0.88	0.46	0.54	FALSE
12	Brain	Plch1	gene expression	ENSRNOG00000009955	0.03	0.02	blup	1085	0.02	3.1e-03	5.1	5.4	7.9e-08	0.87	0.39	0.44	FALSE
13	Brain	Ssr3	gene expression	ENSRNOG00000011148	0.77	0.66	lasso	38	0.68	3.7e-86	5.2	-5.3	9.0e-08	-0.97	0.48	0.52	FALSE
14	Brain	Kcnab1	gene expression	ENSRNOG00000056697	0.36	0.06	lasso	17	0.06	1.6e-06	5.3	-5.5	4.7e-08	-0.94	0.54	0.46	FALSE
15	Brain	Kcnab1	mRNA stability	ENSRNOG00000056697	0.90	0.44	lasso	39	0.47	4.3e-49	5.2	-5.5	3.8e-08	-0.93	0.35	0.65	FALSE
16	Eye	Ssr3	gene expression	ENSRNOG00000011148	0.49	0.34	top1	1	0.34	4.1e-06	5.2	-5.2	1.6e-07	-0.87	0.12	0.06	FALSE
17	Eye	NA	gene expression	ENSRNOG00000069542	0.45	0.14	blup	736	0.20	5.8e-04	5.2	-5.2	2.0e-07	-0.80	0.32	0.45	FALSE
18	Eye	RGD1565059	intron excision ratio	chr2:148400840:148404186	0.37	0.07	top1	1	0.07	3.3e-02	5.1	-5.1	3.3e-07	-0.73	0.06	0.06	FALSE
19	IL	NA	gene expression	ENSRNOG00000069542	0.75	0.16	blup	736	0.33	1.0e-08	5.1	-5.1	2.7e-07	-0.77	0.42	0.58	FALSE
20	IL	Ssr3	mRNA stability	ENSRNOG00000011148	0.29	0.05	blup	1909	0.08	5.9e-03	5.3	-5.3	9.9e-08	-0.98	0.41	0.41	FALSE
21	IL	Kcnab1	mRNA stability	ENSRNOG00000056697	0.86	0.25	lasso	11	0.31	3.4e-08	5.2	-5.4	7.1e-08	-0.91	0.54	0.45	FALSE
22	LHb	Kcnab1	mRNA stability	ENSRNOG00000056697	0.93	0.21	top1	1	0.21	1.2e-05	5.2	-5.2	1.6e-07	-0.76	0.09	0.10	FALSE
23	Liver	Tiparp	gene expression	ENSRNOG00000011238	0.24	0.14	top1	1	0.14	5.1e-15	5.2	5.2	1.6e-07	0.89	0.58	0.42	FALSE
24	Liver	RGD1565059	gene expression	ENSRNOG00000021324	0.06	0.03	blup	1010	0.04	1.5e-05	5.0	5.4	7.5e-08	0.88	0.46	0.53	FALSE
25	Liver	Gmps	gene expression	ENSRNOG00000051151	0.10	0.08	enet	69	0.08	1.9e-09	5.1	5.2	2.5e-07	0.79	0.47	0.53	FALSE
26	Liver	NA	gene expression	ENSRNOG00000069542	0.25	0.21	blup	734	0.21	9.3e-23	5.1	-5.2	1.9e-07	-0.80	0.42	0.58	FALSE
27	Liver	Gmps	isoform ratio	ENSRNOT00000076880	0.03	0.01	blup	860	0.01	1.5e-02	5.1	-5.2	1.6e-07	-0.81	0.36	0.42	FALSE
28	Liver	Slc33a1	mRNA stability	ENSRNOG00000010023	0.07	0.06	blup	851	0.06	4.9e-07	5.1	5.2	2.0e-07	0.79	0.47	0.54	FALSE
29	NAcc2	Ssr3	gene expression	ENSRNOG00000011148	0.53	0.45	lasso	35	0.46	4.1e-27	5.4	-5.5	4.0e-08	-0.83	0.47	0.53	FALSE
30	NAcc2	RGD1565059	isoform ratio	ENSRNOT00000065346	0.05	0.02	blup	1012	0.02	2.0e-02	5.0	-5.3	1.3e-07	-0.83	0.34	0.39	FALSE
31	NAcc2	Gmps	isoform ratio	ENSRNOT00000076292	0.06	0.03	blup	862	0.04	3.6e-03	5.1	5.1	3.3e-07	0.76	0.38	0.44	FALSE
32	NAcc2	Gmps	isoform ratio	ENSRNOT00000084238	0.06	0.03	blup	862	0.04	2.0e-03	5.1	-5.2	2.5e-07	-0.78	0.41	0.47	FALSE
33	OFC	Ssr3	gene expression	ENSRNOG00000011148	0.87	0.39	lasso	4	0.41	8.7e-11	5.4	-5.2	1.9e-07	-0.97	0.40	0.60	FALSE
34	OFC	Vom2r44	gene expression	ENSRNOG00000030104	0.53	0.09	blup	732	0.14	2.9e-04	5.1	5.1	2.9e-07	0.77	0.40	0.54	FALSE
35	OFC	NA	gene expression	ENSRNOG00000069542	0.61	0.19	blup	736	0.22	7.5e-06	5.1	-5.2	2.3e-07	-0.78	0.41	0.57	FALSE
36	OFC	Kcnab1	mRNA stability	ENSRNOG00000056697	0.81	0.08	lasso	14	0.11	1.4e-03	5.1	-5.4	5.1e-08	-0.95	0.47	0.38	FALSE
37	PL	Mme	gene expression	ENSRNOG00000009514	0.28	0.09	lasso	3	0.10	2.6e-03	5.1	-5.2	1.9e-07	-0.83	0.42	0.33	FALSE
38	PL	Ssr3	gene expression	ENSRNOG00000011148	0.87	0.47	top1	1	0.47	1.0e-12	5.4	-5.4	5.4e-08	-0.88	0.33	0.64	FALSE
39	PL	Vom2r44	gene expression	ENSRNOG00000030104	0.52	0.16	lasso	15	0.17	8.9e-05	5.1	5.1	3.1e-07	0.76	0.40	0.55	FALSE
40	PL	NA	gene expression	ENSRNOG00000069542	0.51	0.17	blup	736	0.20	1.7e-05	5.0	-5.1	2.7e-07	-0.77	0.40	0.56	FALSE
41	PL	Kcnab1	mRNA stability	ENSRNOG00000056697	0.57	0.16	lasso	11	0.18	3.7e-05	5.0	-5.4	7.6e-08	-0.88	0.52	0.42	FALSE
42	PL2	Ssr3	gene expression	ENSRNOG00000011148	0.82	0.58	lasso	14	0.60	1.2e-39	5.3	-5.4	7.1e-08	0.97	0.48	0.52	FALSE
43	PL2	Ssr3	mRNA stability	ENSRNOG00000011148	0.16	0.06	top1	1	0.06	3.8e-04	5.3	-5.3	1.1e-07	-0.87	0.18	0.15	FALSE
44	PL2	Kcnab1	mRNA stability	ENSRNOG00000056697	0.80	0.34	top1	1	0.34	3.0e-19	5.3	-5.3	1.2e-07	-0.76	0.27	0.73	FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.