Best TWAS P=2.096778e-07 · Best GWAS P=7.646745e-05 conditioned to 0.5901432
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL | Gtf2h1 | mRNA stability | ENSRNOG00000012360 | 0.52 | 0.33 | enet | 25 | 0.41 | 7.2e-11 | -3.1 | -5.2 | 2.1e-07 | -0.82 | 0.5 | 0.39 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.