Best TWAS P=8.444697e-10 · Best GWAS P=1.525184e-12 conditioned to 0.005697779
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Kit | mRNA stability | ENSRNOG00000002227 | 0.03 | 0.03 | enet | 416 | 0.05 | 4.0e-06 | -6.4 | -6.1 | 8.4e-10 | 0.90 | 0.06 | 0.92 | TRUE |
| 2 | Brain | Exoc1 | mRNA stability | ENSRNOG00000002144 | 0.08 | 0.01 | enet | 16 | 0.05 | 1.8e-05 | 3.6 | -5.7 | 1.1e-08 | 0.60 | 0.48 | 0.42 | TRUE |
| 3 | PL | Exoc1 | mRNA stability | ENSRNOG00000002144 | 0.06 | 0.03 | blup | 2104 | 0.04 | 4.5e-04 | 3.6 | -5.3 | 9.9e-08 | 0.65 | 0.46 | 0.18 | FALSE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.