Best TWAS P=2.674717e-07 · Best GWAS P=0.00467667 conditioned to 0.06724684
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | Hyls1 | gene expression | ENSRNOG00000012980 | 0.47 | 0 | blup | 635 | 0.06 | 9e-08 | 2.2 | -5.1 | 2.7e-07 | -0.77 | 0.02 | 0.02 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.