Best TWAS P=3.79e-19 · Best GWAS P=2.59e-01 conditioned to 1.48e-134
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Stk40 | alternative polyA | XM_006238881.4 | 0.34 | 1115 | 0.13 | 1.2e-14 | -8.18 | 2.93e-16 | 0.04 | FALSE |
| Adipose | Stk40 | alternative polyA | XM_039110152.1 | 0.33 | 1115 | 0.13 | 3.0e-14 | 8.18 | 2.92e-16 | 0.04 | FALSE |
| Adipose | Stk40 | isoform ratio | NM_183056.2 | 0.26 | 1115 | 0.09 | 1.5e-10 | -8.64 | 5.83e-18 | 0.03 | FALSE |
| Adipose | Stk40 | isoform ratio | XM_039110152.1 | 0.33 | 1115 | 0.13 | 1.6e-14 | 7.65 | 2.09e-14 | 0.04 | TRUE |
| Adipose | Ago3 | mRNA stability | Ago3 | 0.11 | 680 | 0.02 | 1.8e-03 | -6.32 | 2.67e-10 | 0 | TRUE |
| Liver | Stk40 | alternative polyA | XM_006238881.4 | 0.46 | 1115 | 0.23 | 1.3e-25 | -8.94 | 3.79e-19 | 0.04 | TRUE |
| Liver | Stk40 | alternative polyA | XM_039110152.1 | 0.47 | 1115 | 0.25 | 1.4e-27 | 8.67 | 4.29e-18 | 0.04 | FALSE |
| Liver | Stk40 | isoform ratio | NM_183056.2 | 0.38 | 1115 | 0.17 | 2.0e-18 | -7.82 | 5.20e-15 | 0.04 | TRUE |