Best TWAS P = 2.71e-22 · Best GWAS P= 2.66e-01 conditioned to 8.93e-15
| Tissue | Gene | RNA modality | RNA phenotype | h2 | # weights | Model R2 | Model R2 P | TWAS Z | TWAS P | Coloc P | Joint |
|---|---|---|---|---|---|---|---|---|---|---|---|
| Adipose | Stk40 | isoform ratio | NM_183056.2 | 0.31 | 1150 | 0.12 | 4.7e-13 | -5.83 | 5.71e-09 | 0.04 | FALSE |
| Adipose | Stk40 | isoform ratio | XM_039110152.2 | 0.38 | 1150 | 0.16 | 2.6e-17 | 5.27 | 1.38e-07 | 0.04 | TRUE |
| Liver | Stk40 | alternative polyA | XM_006238881.5 | 0.35 | 1150 | 0.21 | 1.9e-22 | -9.18 | 4.12e-20 | 0.04 | FALSE |
| Liver | Stk40 | alternative polyA | XM_039110152.2 | 0.38 | 1150 | 0.25 | 1.8e-27 | 9.67 | 4.05e-22 | 0.04 | FALSE |
| Liver | Lsm10 | gene expression | Lsm10 | 0.12 | 1163 | 0.02 | 4.4e-03 | -7.8 | 6.36e-15 | 0 | FALSE |
| Liver | Stk40 | isoform ratio | NM_183056.2 | 0.42 | 1150 | 0.24 | 2.2e-26 | -8.79 | 1.49e-18 | 0.04 | FALSE |
| Liver | Stk40 | isoform ratio | XM_039110152.2 | 0.42 | 1150 | 0.29 | 1.3e-32 | 9.71 | 2.71e-22 | 0.04 | TRUE |