Hub : Traits : tautz: manual_spc7 :

chr9:14,884,566-16,906,451

Best TWAS P=1.592055e-09 · Best GWAS P=2.777223e-10 conditioned to 0.02945335

Associated models

# Tissue Gene Modality RNA phenotype h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 Adipose Supt3h alternative polyA ENSRNOT00000097089 0.05 0.05 enet 37 0.06 6.4e-07 -5.7 5.7 9.1e-09 -0.85 0.55 0.44 FALSE
2 Adipose Supt3h isoform ratio ENSRNOT00000097089 0.07 0.06 blup 1700 0.06 1.9e-07 -5.7 6.0 1.7e-09 -0.87 0.45 0.55 FALSE
3 Brain Supt3h gene expression ENSRNOG00000020153 0.05 0.01 blup 1704 0.03 4.4e-04 -6.3 -6.0 1.6e-09 0.86 0.25 0.70 TRUE
4 Liver Slc29a1 gene expression ENSRNOG00000019752 0.08 0.04 blup 1996 0.05 2.3e-06 -3.8 5.2 1.7e-07 -0.66 0.42 0.58 FALSE
5 Liver Supt3h gene expression ENSRNOG00000020153 0.03 0.02 top1 1 0.02 2.8e-03 -5.7 5.7 1.2e-08 -0.84 0.05 0.03 FALSE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.