Best TWAS P=2.17237e-07 · Best GWAS P=0.02366838 conditioned to 4.211115e-05
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Cd59 | isoform ratio | ENSRNOT00000105770 | 0.13 | 0.01 | enet | 66 | 0.01 | 0.01 | -1.8 | -5.2 | 2.2e-07 | 0.31 | 0.06 | 0.05 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.