Hub : Traits : tautz: manual_spc10 :

chr5:137,682,119-139,250,049

Best TWAS P=3.095094e-24 · Best GWAS P=0.0008112136 conditioned to 0.02738253

Associated models

# Tissue Gene Modality RNA phenotype h2 eQTL R2 model # weights model R2 model R2 P eQTL GWAS Z TWAS Z TWAS P Top SNP corr PP3 PP4 joint
1 Adipose Stk40 intron excision ratio chr5:138406745:138409651 0.20 0.03 blup 1102 0.06 2.2e-07 2.0 -5.7 1.5e-08 -0.40 0.31 0.17 FALSE
2 Adipose Stk40 intron excision ratio chr5:138406745:138412128 0.20 0.03 blup 1102 0.06 5.9e-07 2.0 5.4 6.1e-08 0.33 0.26 0.16 TRUE
3 Liver Map7d1 gene expression ENSRNOG00000010237 0.44 0.18 blup 855 0.29 1.3e-32 1.8 5.8 6.8e-09 0.93 0.40 0.17 FALSE
4 Liver Stk40 mRNA stability ENSRNOG00000025679 0.26 0.04 blup 1102 0.13 2.0e-14 2.2 10.2 3.1e-24 0.51 0.39 0.29 TRUE

h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.