Best TWAS P=1.635918e-09 · Best GWAS P=0.02357473 conditioned to 0.5360161
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Liver | Ccs | gene expression | ENSRNOG00000047816 | 0.07 | 0.05 | enet | 10 | 0.06 | 5.1e-07 | -0.45 | -6 | 1.6e-09 | -0.47 | 0.04 | 0.02 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.