Best TWAS P=3.156533e-07 · Best GWAS P=0.0002939547 conditioned to 0.007296088
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Liver | Rap2b | gene expression | ENSRNOG00000065432 | 0.03 | 0.02 | enet | 13 | 0.03 | 0.00085 | -3.5 | -5.1 | 3.2e-07 | 0.19 | 0.57 | 0.33 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.