Best TWAS P=8.857035e-08 · Best GWAS P=0.00107692 conditioned to 0.4329973
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Lamp1 | alternative TSS | ENSRNOT00000105987 | 0.24 | 0.02 | blup | 1587 | 0.04 | 0.00001 | 2.9 | 5.2 | 2.4e-07 | 0.81 | 0.24 | 0.28 | FALSE |
| 2 | Liver | AC117058.1 | gene expression | ENSRNOG00000045729 | 0.15 | 0.00 | blup | 1793 | 0.01 | 0.01100 | -1.8 | 5.3 | 8.9e-08 | 0.48 | 0.08 | 0.08 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.