Best TWAS P=2.12864e-08 · Best GWAS P=3.616115e-07 conditioned to 0.06087283
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | PL2 | Cand2 | gene expression | ENSRNOG00000010473 | 0.17 | 0.14 | enet | 117 | 0.2 | 2.9e-11 | -4.2 | 5.6 | 2.1e-08 | -0.66 | 0.57 | 0.43 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.