Best TWAS P=2.351783e-08 · Best GWAS P=0.01644935 conditioned to 1.704518e-08
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Brain | AABR07017874.1 | gene expression | ENSRNOG00000042156 | 0.13 | 0.03 | enet | 31 | 0.04 | 0.00012 | -1.7 | 5.6 | 2.4e-08 | -0.89 | 0 | 0.01 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.