Best TWAS P=2.454257e-09 · Best GWAS P=0.02710863 conditioned to 1.75216e-10
# | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
1 | Adipose | Snx16 | gene expression | ENSRNOG00000009953 | 0.11 | 0.04 | enet | 157 | 0.06 | 1.2e-07 | -1.3 | -6 | 2.5e-09 | 0.88 | 0.14 | 0.1 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.