Best TWAS P=1.89564e-09 · Best GWAS P=0.02998186 conditioned to 0.2490693
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Cd59 | isoform ratio | ENSRNOT00000105770 | 0.13 | 0.01 | enet | 66 | 0.01 | 0.01 | 0.18 | 6 | 1.9e-09 | -0.52 | 0.04 | 0.02 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.