Best TWAS P=3.475487e-07 · Best GWAS P=0.01221609 conditioned to 2.446277e-06
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Adipose | Ddx25 | gene expression | ENSRNOG00000012260 | 0.7 | 0.01 | lasso | 17 | 0.03 | 0.00035 | -1.1 | 5.1 | 3.5e-07 | -0.9 | 0.01 | 0.02 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.