chr5:152,510,403-154,082,317

Trait: Delay discounting total patch changes 18 sec

Best TWAS P=9.54e-08 · Best GWAS P=7.86e-08 conditioned to 1e+00

Associated models

Tissue	Gene	RNA modality	RNA phenotype	h²	# weights	Model R²	Model R² P	TWAS Z	TWAS P	Coloc P	Joint
Adipose	Sdhb	isoform ratio	ENSRNOT00000105563	0.6	32	0.34	1.1e-38	5.2	1.98e-07	0.87	FALSE
BLA	Sdhb	alternative polyA	ENSRNOT00000098351	0.8	70	0.59	1.7e-38	-5.1	3.36e-07	0.89	FALSE
BLA	Sdhb	alternative polyA	ENSRNOT00000098351	0.78	28	0.58	2.5e-37	-5.15	2.60e-07	0.89	FALSE
BLA	Sdhb	alternative polyA	ENSRNOT00000105563	0.82	61	0.6	3.2e-39	5.1	3.41e-07	0.89	FALSE
Brain	Sdhb	alternative polyA	ENSRNOT00000098351	0.79	9	0.66	3.3e-81	-5.13	2.97e-07	0.89	FALSE
Brain	Sdhb	alternative polyA	ENSRNOT00000105563	0.77	1	0.64	1.6e-77	5.17	2.29e-07	0.84	FALSE
Brain	Sdhb	alternative polyA	ENSRNOT00000098351	0.77	21	0.65	2.8e-78	-5.11	3.30e-07	0.89	FALSE
Brain	Sdhb	alternative polyA	ENSRNOT00000105563	0.75	10	0.63	3.5e-75	5.11	3.24e-07	0.89	FALSE
Brain	Sdhb	isoform ratio	ENSRNOT00000105563	0.66	19	0.53	3.2e-57	5.16	2.42e-07	0.89	FALSE
IL	Sdhb	alternative polyA	ENSRNOT00000098351	0.59	4	0.3	4.6e-08	-5.17	2.34e-07	0.77	TRUE
IL	Sdhb	alternative polyA	ENSRNOT00000105563	0.58	2	0.3	4.5e-08	5.21	1.90e-07	0.76	TRUE
IL	Sdhb	alternative polyA	ENSRNOT00000098351	0.53	1	0.32	2.0e-08	-5.26	1.47e-07	0.64	FALSE
IL	Sdhb	alternative polyA	ENSRNOT00000105563	0.5	1	0.3	7.3e-08	5.26	1.47e-07	0.54	FALSE
IL	Sdhb	isoform ratio	ENSRNOT00000105563	0.59	1	0.24	1.6e-06	5.11	3.14e-07	0.22	FALSE
LHb	Sdhb	alternative polyA	ENSRNOT00000105563	0.55	1	0.36	2.3e-09	5.15	2.61e-07	0.67	FALSE
Liver	Sdhb	alternative polyA	ENSRNOT00000105563	0.36	17	0.34	4.8e-39	5.14	2.77e-07	0.85	FALSE
Liver	Sdhb	gene expression	ENSRNOG00000007967	0.16	1	0.07	4.3e-08	-5.34	9.54e-08	0.92	TRUE
Liver	Sdhb	isoform ratio	ENSRNOT00000105563	0.14	1	0.12	4.4e-13	5.29	1.24e-07	0.9	FALSE
Liver	Sdhb	mRNA stability	ENSRNOG00000007967	0.1	1	0.1	7.7e-11	-5.12	3.07e-07	0.8	FALSE
NAcc	Sdhb	alternative polyA	ENSRNOT00000098351	0.73	1	0.59	2.5e-53	-5.29	1.24e-07	0.9	FALSE
NAcc	Sdhb	alternative polyA	ENSRNOT00000105563	0.78	19	0.63	2.9e-60	5.14	2.78e-07	0.9	FALSE
NAcc	Sdhb	alternative polyA	ENSRNOT00000098351	0.75	1	0.58	8.9e-53	-5.29	1.24e-07	0.9	FALSE
NAcc	Sdhb	alternative polyA	ENSRNOT00000105563	0.79	14	0.62	2.9e-58	5.14	2.77e-07	0.9	FALSE
NAcc	Sdhb	gene expression	ENSRNOG00000007967	0.19	9	0.14	2.1e-10	-5.11	3.21e-07	0.86	FALSE
NAcc	Sdhb	isoform ratio	ENSRNOT00000105563	0.64	1	0.53	6.0e-46	5.29	1.24e-07	0.9	FALSE
OFC	Sdhb	alternative polyA	ENSRNOT00000098351	0.65	1	0.33	9.7e-09	-5.15	2.61e-07	0.74	FALSE
OFC	Sdhb	alternative polyA	ENSRNOT00000105563	0.63	1	0.33	1.5e-08	5.15	2.61e-07	0.73	FALSE
OFC	Sdhb	alternative polyA	ENSRNOT00000098351	0.59	1	0.31	4.1e-08	-5.15	2.61e-07	0.7	FALSE
OFC	Sdhb	alternative polyA	ENSRNOT00000105563	0.58	1	0.31	3.1e-08	5.15	2.61e-07	0.69	FALSE
OFC	Padi2	gene expression	ENSRNOG00000007574	0.26	1	0.16	1.4e-04	5.26	1.47e-07	0.14	TRUE
OFC	Sdhb	isoform ratio	ENSRNOT00000010593	0.28	1	0.06	1.2e-02	-5.15	2.61e-07	0.06	FALSE
OFC	Sdhb	isoform ratio	ENSRNOT00000105563	0.5	8	0.23	4.4e-06	5.1	3.33e-07	0.6	FALSE
PL	Sdhb	alternative polyA	ENSRNOT00000098351	0.8	31	0.65	1.2e-63	-5.1	3.35e-07	0.9	FALSE
PL	Padi2	gene expression	ENSRNOG00000007574	0.58	34	0.47	3.9e-40	5.14	2.78e-07	0.87	FALSE
PL	Sdhb	isoform ratio	ENSRNOT00000010593	0.34	1	0.27	2.7e-20	-5.17	2.29e-07	0.84	FALSE
PL	Sdhb	isoform ratio	ENSRNOT00000105563	0.65	1	0.52	1.5e-45	5.32	1.03e-07	0.92	FALSE
PL	Crocc	mRNA stability	ENSRNOG00000008334	0.06	20	0.07	2.6e-06	-5.2	2.01e-07	0.74	FALSE
PL	Necap2	mRNA stability	ENSRNOG00000008427	0.08	1	0.05	1.1e-04	-5.13	2.89e-07	0.25	FALSE