Best TWAS P=1.369109e-08 · Best GWAS P=7.893586e-06 conditioned to 2.011057e-86
| # | Tissue | Gene | Modality | RNA phenotype | h2 | eQTL R2 | model | # weights | model R2 | model R2 P | eQTL GWAS Z | TWAS Z | TWAS P | Top SNP corr | PP3 | PP4 | joint |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | PL | Tcp11l1 | mRNA stability | ENSRNOG00000042576 | 0.09 | 0.1 | enet | 200 | 0.13 | 4.8e-10 | -4.5 | 5.7 | 1.4e-08 | -0.88 | 0.36 | 0.64 | TRUE |
h2: Heritability estimate for the given transcriptomic model. PP3: Posterior probability of two distinct causal variants. PP4: Posterior probability of a single shared causal variant. joint: Whether the RNA phenotype is in the joint model.